TRIF TIR Filament Cryo-EM Structure
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dk8
Q-score: 0.47
Rat alpha5beta1 integrin, headpiece
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8oxz
Q-score: 0.293
Shafaq-Zadah M, Dransart E, Wunder C, Chambon V, Valades-Cruz CA, Leconte L, Sarangi NK, Robinson J, Bai S-K, Regmi R, Di Cicco A, Hovasse A, Bartels R, Nilsson UJ, Cianferani-Sanglier S, Leffler H, Keyes TE, Levy D, Raunser S, Roderer D, Johannes L
To Be Published
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Alpha5beta1 integrin from rattus norvegicus (Complex from Rattus norvegicus)
- Integrin subunit alpha 5 (119 kDa, Protein from Rattus norvegicus)
- Integrin beta-1 (88 kDa, Protein from Rattus norvegicus)
Rat alpha5beta1 integrin, leg piece
Shafaq-Zadah M, Dransart E, Wunder C, Chambon V, Valades-Cruz CA, Leconte L, Sarangi NK, Robinson J, Bai S-K, Regmi R, Di Cicco A, Hovasse A, Bartels R, Nilsson UJ, Cianferani-Sanglier S, Leffler H, Keyes TE, Levy D, Raunser S, Roderer D, Johannes L
To Be Published
Cryo-EM structure of the phalloidin-bound pointed end of the actin filament.
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 9fjm
Q-score: 0.476
Boiero Sanders M, Oosterheert W, Hofnagel O, Bieling P, Raunser S
Nat Commun (2024) 15 pp. 7969-7969 [ DOI: doi:10.1038/s41467-024-52251-3 Pubmed: 39261469 ]
- Magnesium ion (24 Da, Ligand)
- Phalloidin (Complex from Amanita phalloides)
- Actin filament pointed end (Complex from Homo sapiens)
- Actin filament pointed end bound by phalloidin (Complex)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
Structure of the undecorated pointed end of F-actin
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 9fjo
Q-score: 0.543
Boiero Sanders M, Oosterheert W, Hofnagel O, Bieling P, Raunser S
Nat Commun (2024) 15 pp. 7969-7969 [ DOI: doi:10.1038/s41467-024-52251-3 Pubmed: 39261469 ]
- Magnesium ion (24 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex of actin subunits that form the pointed end of actin filaments. (Complex from Oryctolagus cuniculus)
Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1)
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 9fju
Q-score: 0.399
Boiero Sanders M, Oosterheert W, Hofnagel O, Bieling P, Raunser S
Nat Commun (2024) 15 pp. 7969-7969 [ DOI: doi:10.1038/s41467-024-52251-3 Pubmed: 39261469 ]
- Magnesium ion (24 Da, Ligand)
- Phalloidin (Complex from Amanita phalloides)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin filament pointed end (Complex from Bos taurus)
- Phosphate ion (94 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Two dnase i molecules, each bound to the ultimate and penultimate actin subunits of the f-actin pointed end. (Complex from Bos taurus)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Bos taurus)
- Deoxyribonuclease-1 (31 kDa, Protein from Bos taurus)
- F-actin pointed end bound by dnase i and phalloidin. (Complex)
Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2).
Resolution: 3.79 Å
EM Method: Single-particle
Fitted PDBs: 9fjy
Q-score: 0.412
Boiero Sanders M, Oosterheert W, Hofnagel O, Bieling P, Raunser S
Nat Commun (2024) 15 pp. 7969-7969 [ DOI: doi:10.1038/s41467-024-52251-3 Pubmed: 39261469 ]
- Magnesium ion (24 Da, Ligand)
- Phalloidin (Complex from Amanita phalloides)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin filament pointed end (Complex from Bos taurus)
- Phosphate ion (94 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Two dnase i molecules, each bound to the ultimate and penultimate actin subunits of the f-actin pointed end. (Complex from Bos taurus)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Bos taurus)
- Deoxyribonuclease-1 (31 kDa, Protein from Bos taurus)
- F-actin pointed end bound by dnase i and phalloidin. (Complex)
Structure of the Lifeact13-F-actin complex
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8pvx
Q-score: 0.444
To Be Published
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Lifeact13 (1 kDa, Protein from Saccharomyces cerevisiae)
- The complex between skeletal actin from rabbit and lifeact13 (Complex)
- Lifeact13 (Complex from Saccharomyces cerevisiae)
- Actin, alpha skeletal muscle (Complex from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin.
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8rtt
Q-score: 0.444
Oosterheert W, Boiero Sanders M, Funk J, Prumbaum D, Raunser S, Bieling P
Science (2024) 384 pp. eadn9560-eadn9560 [ Pubmed: 38603491 DOI: doi:10.1126/science.adn9560 ]
- Magnesium ion (24 Da, Ligand)
- Actin, cytoplasmic 1, n-terminally processed (41 kDa, Protein from Homo sapiens)
- Cell division control protein 12 (48 kDa, Protein from Schizosaccharomyces pombe)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Phalloidin. (Complex from Amanita phalloides)
- Complex of the dimeric fh2 domain of s. pombe cdc12 bound to the barbed end of phalloidin stabilized f-actin. (Complex)
- Dimeric fh2 domain of s. pombe cdc12 (Complex from Schizosaccharomyces pombe)
- Actin filament (Complex from Homo sapiens)