Cryo-EM structure of F-actin stabilized by cis-optoJASP-8
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ahn
Q-score: 0.553
Pospich S, Kullmer F, Nasufovic V, Funk J, Belyy A, Bieling P, Arndt HD, Raunser S
Angew Chem Int Ed Engl (2021) 60 pp. 8678-8682 [ Pubmed: 33449370 DOI: doi:10.1002/anie.202013193 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- ~{n}-[4-[(4~{r},7~{r},10~{s},13~{s},15~{e},19~{s})-4-(4-hydroxyphenyl)-7-(1~{h}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-2,6,9,12-tetrakis(oxidanylidene)-1-oxa-5,8,11-triazacyclononadec-15-en-10-yl]butyl]-~{n}'-[5-methoxy-2-[(~{z})-(3,4,5-trimethoxyphenyl)diazenyl]phenyl]butanediamide (1 kDa, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Filamentous alpha actin stabilized by cis-optojasp-8 in complex with adp-pi (Complex from Oryctolagus cuniculus)
- Actin, alpha skeletal muscle (42 kDa, Protein from Rabbit)
Cryo-EM structure of F-actin stabilized by trans-optoJASP-8
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7ahq
Q-score: 0.46
Pospich S, Kullmer F, Nasufovic V, Funk J, Belyy A, Bieling P, Arndt HD, Raunser S
Angew Chem Int Ed Engl (2021) 60 pp. 8678-8682 [ Pubmed: 33449370 DOI: doi:10.1002/anie.202013193 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- ~{n}-[4-[(4~{r},7~{r},10~{s},13~{s},15~{e},19~{s})-4-(4-hydroxyphenyl)-7-(1~{h}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-2,6,9,12-tetrakis(oxidanylidene)-1-oxa-5,8,11-triazacyclononadec-15-en-10-yl]butyl]-~{n}'-[5-methoxy-2-[(~{z})-(3,4,5-trimethoxyphenyl)diazenyl]phenyl]butanediamide (1 kDa, Ligand)
- Actin, alpha skeletal muscle (42 kDa, Protein from Rabbit)
- Filamentous alpha actin stabilized by trans-optojasp-8 in complex with adp-pi (Complex from Oryctolagus cuniculus)
Cryo-EM structure of F-actin in complex with ADP
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 5onv
Q-score: 0.372
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Filamentous alpha actin in complex with adp (Complex from Oryctolagus cuniculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5ooc
Q-score: 0.449
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Filamentous jasplakinolide-stabilized alpha actin in complex with adp (Complex from Oryctolagus cuniculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- (4~{r},7~{r},10~{s},13~{s},15~{e},19~{s})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{h}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone (673 Da, Ligand)
Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-Pi
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 5ood
Q-score: 0.424
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Phosphate ion (94 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- Filamentous jasplakinolide-stabilized alpha actin in complex with adp-pi (Complex from Oryctolagus cuniculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- (4~{r},7~{r},10~{s},13~{s},15~{e},19~{s})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{h}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone (673 Da, Ligand)
Cryo-EM structure of F-actin in complex with AppNHp (AMPPNP)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5ooe
Q-score: 0.457
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- Filamentous alpha actin in complex with appnhp (amppnp) (Complex from Oryctolagus cuniculus)
Cryo-EM structure of F-actin in complex with ADP-BeFx
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 5oof
Q-score: 0.478
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Magnesium ion (24 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Filamentous alpha actin in complex with adp-befx (Complex from Oryctolagus cuniculus)
Cryo-EM structure of F-actin in complex with ADP-Pi
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6fhl
Q-score: 0.497
Merino F, Pospich S, Funk J, Wagner T, Kullmer F, Arndt HD, Bieling P, Raunser S
Nat Struct Mol Biol (2018) 25 pp. 528-537 [ DOI: doi:10.1038/s41594-018-0074-0 Pubmed: 29867215 ]
- Filamentous alpha actin in complex with adp-adppi (Complex from Oryctolagus cuniculus)
- Phosphate ion (94 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rabbit)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)