Ca2+ bound Drosophila Slo channel
Resolution: 2.38 Å
EM Method: Single-particle
Fitted PDBs: 7pxe
Q-score: 0.604
Raisch T, Brockmann A, Ebbinghaus-Kintscher U, Freigang J, Gutbrod O, Kubicek J, Maertens B, Hofnagel O, Raunser S
Nat Commun (2021) 12 pp. 7164-7164 [ Pubmed: 34887422 DOI: doi:10.1038/s41467-021-27435-w ]
- Slo tetramer (Complex from Drosophila melanogaster)
- Water (18 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Isoform j of calcium-activated potassium channel slowpoke (130 kDa, Protein from Drosophila melanogaster)
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
Ca2+ free Drosophila Slo channel
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 7pxf
Q-score: 0.485
Raisch T, Brockmann A, Ebbinghaus-Kintscher U, Freigang J, Gutbrod O, Kubicek J, Maertens B, Hofnagel O, Raunser S
Nat Commun (2021) 12 pp. 7164-7164 [ Pubmed: 34887422 DOI: doi:10.1038/s41467-021-27435-w ]
- Isoform j of calcium-activated potassium channel slowpoke (130 kDa, Protein from Drosophila melanogaster)
- Slo tetramer (Complex from Drosophila melanogaster)
- Potassium ion (39 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Verruculogen-bound Drosophila Slo channel
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 7pxg
Q-score: 0.552
Raisch T, Brockmann A, Ebbinghaus-Kintscher U, Freigang J, Gutbrod O, Kubicek J, Maertens B, Hofnagel O, Raunser S
Nat Commun (2021) 12 pp. 7164-7164 [ Pubmed: 34887422 DOI: doi:10.1038/s41467-021-27435-w ]
- Slo tetramer (Complex from Drosophila melanogaster)
- Calcium ion (40 Da, Ligand)
- Verruculogen (511 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Isoform j of calcium-activated potassium channel slowpoke (130 kDa, Protein from Drosophila melanogaster)
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
Emodepside-bound Drosophila Slo channel
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 7pxh
Q-score: 0.569
Raisch T, Brockmann A, Ebbinghaus-Kintscher U, Freigang J, Gutbrod O, Kubicek J, Maertens B, Hofnagel O, Raunser S
Nat Commun (2021) 12 pp. 7164-7164 [ Pubmed: 34887422 DOI: doi:10.1038/s41467-021-27435-w ]
- Slo tetramer (Complex from Drosophila melanogaster)
- (3~{s},6~{r},9~{s},12~{r},15~{s},18~{r},21~{s},24~{r})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone (1 kDa, Ligand)
- Calcium ion (40 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Isoform j of calcium-activated potassium channel slowpoke (130 kDa, Protein from Drosophila melanogaster)
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)