Human BBsome core complex with subunits BBS1, BBS4, BBS5, BBS8, BBS9, BBS18
Klink BU, Zent E, Juneja P, Kuhlee A, Raunser S, Wittinghofer A
eLife (2017) 6 [ DOI: doi:10.7554/eLife.27434 Pubmed: 29168691 ]
- A 6subunit, bbsome complex. (330 kDa, Complex from Homo sapiens)
Negative stain reconstruction of the ROD(1-1250):Zwilch:ZW10
Mosalaganti S, Keller J, Altenfeld A, Winzker M, Rombaut P, Saur M, Petrovic A, Wehenkel A, Wohlgemuth S, Muller F, Maffini S, Bange T, Herzog F, Waldmann H, Raunser S, Musacchio A
J Cell Biol (2017) 216 pp. 961-981 [ Pubmed: 28320825 DOI: doi:10.1083/jcb.201611060 ]
Negative stain EM structure of the Tse6-Tsi6-VgrG1-EF-Tu complex in detergent
Whitney J, Quentin D, Sawai S, LeRoux M, Harding B, Ledvina H, Tran B, Robinson H, Goo YA, Goodlett D, Raunser S, Mougous J
Cell (2015) 163 pp. 607-619 [ Pubmed: 26456113 DOI: doi:10.1016/j.cell.2015.09.027 ]
- Elongation factor tu 1 (43 kDa, Protein from Escherichia coli)
- Valine-glycine repeat protein 1 (72 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Tse6-tsi6-vgrg1-ef-tu complex in detergent (331 kDa, Sample)
- Type vi secretion immunity 6 (11 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Type vi secretion exported 6 (45 kDa, Protein from Pseudomonas aeruginosa PAO1)
Negative stain EM structure of the Tse6-Tsi6-VgrG1-EagT6-EF-Tu complex
Whitney J, Quentin D, Sawai S, LeRoux M, Harding B, Ledvina H, Tran B, Robinson H, Goo YA, Goodlett D, Raunser S, Mougous J
Cell (2015) 163 pp. 607-619 [ Pubmed: 26456113 DOI: doi:10.1016/j.cell.2015.09.027 ]
- Tse6-tsi6-vgrg1-eagt6-ef-tu complex (364 kDa, Sample)
- Elongation factor tu 1 (43 kDa, Protein from Escherichia coli)
- Effector associated gene with tse6 (16 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Valine-glycine repeat protein 1 (72 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Type vi secretion immunity 6 (11 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Type vi secretion exported 6 (45 kDa, Protein from Pseudomonas aeruginosa PAO1)
3D structure of the KMN network
Petrovic A, Mosalaganti S, Keller J, Mattiuzzo M, Overlack K, Krenn V, De Antoni A, Wohlgemuth S, Cecatiello V, Pasqualato S, Raunser S, Musacchio A
Mol Cell (2014) 53 pp. 591-605 [ Pubmed: 24530301 DOI: doi:10.1016/j.molcel.2014.01.019 ]
- Bub-linking kinetochore protein (30 kDa, Protein from Homo sapiens)
- Kmn network reconstituted as follows: human mis12complex bound to ndc80complex (bonsai) and knl1( from amino acids, 2106-2316) (200 kDa, Sample)
- Highly expressed in cancer-1 (25 kDa, Protein from Homo sapiens)
- Nsl1 (20 kDa, Protein from Homo sapiens)
- Mis12 (20 kDa, Protein from Homo sapiens)
- Polyamine-modulated factor 1 (20 kDa, Protein from Homo sapiens)
- Dsn1 (40 kDa, Protein from Homo sapiens)
- Spc24 (9 kDa, Protein from Homo sapiens)
- Spc25 (10 kDa, Protein from Homo sapiens)
- Cell division cycle-assoiciated protein1 (20 kDa, Protein from Homo sapiens)
Negative stain EM structure of the PTC3 holotoxin complex (TcdA1, TcdB2, TccC3) in prepore state
Gatsogiannis C, Lang AE, Meusch D, Pfaumann V, Hofnagel O, Benz R, Aktories K, Raunser S
Nature (2013) 495 pp. 520-523 [ DOI: doi:10.1038/nature11987 Pubmed: 23515159 ]
- Tccc3 (109 kDa, Protein from Photorhabdus luminescens)
- Ptc3 (tcda1, tcdb2, tccc3) (1 MDa, Sample)
- Tcdb2 (166 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Negative stain EM structure of the PTC3 holotoxin complex (TcdA1, TcdB2, TccC3) in pore state
Gatsogiannis C, Lang AE, Meusch D, Pfaumann V, Hofnagel O, Benz R, Aktories K, Raunser S
Nature (2013) 495 pp. 520-523 [ DOI: doi:10.1038/nature11987 Pubmed: 23515159 ]
- Tccc3 (109 kDa, Protein from Photorhabdus luminescens)
- Ptc3 (tcda1, tcdb2, tccc3) (1 MDa, Sample)
- Tcdb2 (166 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Negative stain EM structure of TcdA1 in pore state
Gatsogiannis C, Lang AE, Meusch D, Pfaumann V, Hofnagel O, Benz R, Aktories K, Raunser S
Nature (2013) 495 pp. 520-523 [ DOI: doi:10.1038/nature11987 Pubmed: 23515159 ]
- Tcda1 (1 MDa, Sample)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Negative stain EM structure of the HOPS tethering complex (conformation 1)
Broecker C, Kuhlee A, Gatsogiannis C, Balderhaar HJ, Hoenscher C, Engelbrecht-Vandre S, Ungermann C, Raunser S
PNAS (2012) 109 pp. 1991-1996 [ Pubmed: 22308417 DOI: doi:10.1073/pnas.1117797109 ]
- Vacuolar protein sorting-associated protein 33 (Protein from Saccharomyces cerevisiae)
- Vacuolar protein sorting-associated protein 18 (Protein from Saccharomyces cerevisiae)
- Vacuolar protein sorting-associated protein 11 (Protein from Saccharomyces cerevisiae)
- Vacuole protein sorting (hops) tethering complex containing vps11, vps16, vps18, vps33, vp39, vps41 (700 kDa, Sample)
- Vacuolar protein sorting-associated protein 16 (Protein from Saccharomyces cerevisiae)
- Vacuolar protein sorting-associated protein 41 (Protein from Saccharomyces cerevisiae)
- Vacuolar protein sorting-associated protein 39 (Protein from Saccharomyces cerevisiae)