TBOA-bound GltPh RSMR mutant in IFS state
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 7ug0
Q-score: 0.596
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ DOI: doi:10.1021/jacs.3c01003 ]
- (3s)-3-(benzyloxy)-l-aspartic acid (239 Da, Ligand)
- Water (18 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
- Rsmr mutant bound with na/tboa (44 MDa, Cellular component from Pyrococcus horikoshii)
Asp-bound GltPh RSMR mutant in IFS-A1 state
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 7ugd
Q-score: 0.534
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ DOI: doi:10.1021/jacs.3c01003 ]
- Aspartic acid (133 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Gltph (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
TBOA-bound GltPh RSMR mutant in OFS state
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7ugj
Q-score: 0.531
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ DOI: doi:10.1021/jacs.3c01003 ]
- (3s)-3-(benzyloxy)-l-aspartic acid (239 Da, Ligand)
- Tboa-bound gltph rsmr mutant in ofs state (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
Asp-bound GltPh RSMR mutant in IFS-A2 state
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 7ugv
Q-score: 0.532
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ Pubmed: 37023263 DOI: doi:10.1021/jacs.3c01003 ]
- Aspartic acid (133 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Gltph (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
Asp-bound GltPh RSMR mutant in IFS-B1 state
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 7ugx
Q-score: 0.499
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ Pubmed: 37023263 DOI: doi:10.1021/jacs.3c01003 ]
- Aspartic acid (133 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Gltph rsmr mutant bound with na and asp (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
Asp-bound GltPh RSMR mutant in iOFS state
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 7uh3
Q-score: 0.463
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ DOI: doi:10.1021/jacs.3c01003 ]
- Aspartic acid (133 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Gltph rsmr mutant bound with na and asp (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
Asp-bound GltPh RSMR mutant in IFS-B2 state
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7uh6
Q-score: 0.402
Huang Y, Reddy KD, Bracken C, Qiu B, Zhan W, Eliezer D, Boudker O
J Am Chem Soc (2023) 145 pp. 8583-8592 [ DOI: doi:10.1021/jacs.3c01003 ]
- Aspartic acid (133 Da, Ligand)
- Glutamate transporter homolog (44 kDa, Protein from Pyrococcus horikoshii)
- Gltph rsmr mutant bound with na and asp (Complex from Pyrococcus horikoshii)
- Sodium ion (22 Da, Ligand)
GltPh mutant (S279E/D405N) in complex with aspartate and sodium ions
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 7rcp
Q-score: 0.701
Reddy KD, Ciftci D, Scopelliti AJ, Boudker O
J Gen Physiol (2022) 154 [ DOI: doi:10.1085/jgp.202213131 Pubmed: 35452090 ]
- Water (18 Da, Ligand)
- Aspartic acid (133 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Complex of glutamate transporter homologue gltph mutant (s279e/d405n) with sodium nitrate and aspartate (Cellular component from Pyrococcus horikoshii)
- Glutamate transporter homolog (43 kDa, Protein from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3))