Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K1179W mutant
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8cpz
Q-score: 0.526
Ng'ang'a PN, Folz J, Kucher S, Roderer D, Xu Y, Sitsel O, Belyy A, Prumbaum D, Kuhnemuth R, Assafa TE, Dong M, Seidel CAM, Bordignon E, Raunser S
Sci Adv (2025) 11 pp. eadr2019-eadr2019 [ Pubmed: 39752508 DOI: doi:10.1126/sciadv.adr2019 ]
- Tcda1 (285 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (1 MDa, Complex from Photorhabdus luminescens)
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K567W K2008W mutant
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cq0
Q-score: 0.466
Ng'ang'a PN, Folz J, Kucher S, Roderer D, Xu Y, Sitsel O, Belyy A, Prumbaum D, Kuhnemuth R, Assafa TE, Dong M, Seidel CAM, Bordignon E, Raunser S
Sci Adv (2025) 11 pp. eadr2019-eadr2019 [ Pubmed: 39752508 DOI: doi:10.1126/sciadv.adr2019 ]
- Tcda1 (285 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (1 MDa, Complex from Photorhabdus luminescens)
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, C16S, C20S, C870S, T1279C mutant
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8cq2
Q-score: 0.448
Ng'ang'a PN, Folz J, Kucher S, Roderer D, Xu Y, Sitsel O, Belyy A, Prumbaum D, Kuhnemuth R, Assafa TE, Dong M, Seidel CAM, Bordignon E, Raunser S
Sci Adv (2025) 11 pp. eadr2019-eadr2019 [ Pubmed: 39752508 DOI: doi:10.1126/sciadv.adr2019 ]
- Tcda1 (285 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (1 MDa, Complex from Photorhabdus luminescens)
Structure of Photorhabdus luminescens Tc holotoxin pore, Mutation TccC3-D651A
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6sue
Q-score: 0.385
Roderer D, Hofnagel O, Benz R, Raunser S
PNAS (2019) 116 pp. 23083-23090 [ DOI: doi:10.1073/pnas.1909821116 Pubmed: 31666324 ]
- Tcdb2,tccc3 (274 kDa, Protein from Photorhabdus luminescens)
- Tc holotoxin composed of the tcda1 pentamer and tcdb2-tccc3 (1 MDa, Complex from Photorhabdus luminescens)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Structure of Photorhabdus luminescens Tc holotoxin pore
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6suf
Q-score: 0.396
Roderer D, Hofnagel O, Benz R, Raunser S
PNAS (2019) 116 pp. 23083-23090 [ DOI: doi:10.1073/pnas.1909821116 Pubmed: 31666324 ]
- Tc holotoxin complex in the pore form, formed by the tcda1 pentamer and tcdb2-tccc3 (1 MDa, Complex from Photorhabdus luminescens)
- Tcdb2,tccc3 (274 kDa, Protein from Photorhabdus luminescens)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Cryo-EM structure of Photorhabdus luminescens TcdA1
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 6rw6
Q-score: 0.585
Leidreiter F, Roderer D, Meusch D, Gatsogiannis C, Benz R, Raunser S
Sci Adv (2019) 5 pp. eaax6497-eaax6497 [ Pubmed: 31663026 DOI: doi:10.1126/sciadv.aax6497 ]
- Tcda1 pentamer (1 MDa, Complex from Photorhabdus luminescens)
- Tcda1 (283 kDa, Protein from Photorhabdus luminescens)
Cryo-EM structure of Photorhabdus luminescens TcdA4
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6rwa
Q-score: 0.352
Leidreiter F, Roderer D, Meusch D, Gatsogiannis C, Benz R, Raunser S
Sci Adv (2019) 5 pp. eaax6497-eaax6497 [ Pubmed: 31663026 DOI: doi:10.1126/sciadv.aax6497 ]
- P. luminescens tcda4 pentamer (1 MDa, Complex from Photorhabdus luminescens)
- Tcda4 (270 kDa, Protein from Photorhabdus luminescens)