Microtubule protofilament reconstruction in CCP5:microtubule class#1 complex
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
Microtubule protofilament reconstruction in CCP5:microtubule class#2 complex
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
Microtubule Protofilament reconstruction in CCP5:microtubule class#3 complex
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8v3q
Q-score: 0.542
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
- Zinc ion (65 Da, Ligand)
- Beta tubulin tail (827 Da, Protein from Sus scrofa)
- Ccp5 in complex with beta tubulin tail (Complex)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8v3r
Q-score: 0.49
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
- Beta tubulin tail (487 Da, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ccp5 in complex with beta tubulin tail (Complex)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8v3s
Q-score: 0.456
Chen J, Zehr EA, Gruschus JM, Szyk A, Liu Y, Tanner ME, Tjandra N, Roll-Mecak A
Nature (2024) 631 pp. 905-912 [ DOI: doi:10.1038/s41586-024-07699-0 Pubmed: 39020174 ]
- Beta tubulin tail (487 Da, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ccp5 in complex with beta tubulin tail (Complex)
- Cytosolic carboxypeptidase-like protein 5 (68 kDa, Protein from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9bp6
Q-score: 0.503
bioRxiv (2023) [ DOI: doi:10.1101/2023.12.01.569594 ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin beta chain (49 kDa, Protein from Homo sapiens)
- Tubulin alpha-1b chain (50 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Alpha1b and betai/ivb microtubule (300 kDa, Complex from Homo sapiens)
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
- Tubulin alpha-1b chain (Protein from Homo sapiens)
- Tubulin polyglutamylase ttll6 (Protein from Mus musculus)
- Ttll6 bound to unmodified human microtubules (300 kDa, Complex)
- Tubulin beta-i/ivb chain (Protein from Homo sapiens)
- Tubulin polyglutamylase ttll6 (Complex from Mus musculus)
- Tubulin alpha-1b, betai and betaivb (Complex from Homo sapiens)
Map of Tubulin Tyrosine Ligase Like 6
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) 20 pp. 1493-1504 [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
Composite map of TTLL6 bound to unmodified human microtubule
Mahalingan KK, Grotjahn DA, Li Y, Lander GC, Zehr EA, Roll-Mecak A
Nat Chem Biol (2024) 20 pp. 1493-1504 [ DOI: doi:10.1038/s41589-024-01599-0 Pubmed: 38658656 ]
- Tubulin alpha-1b chain (Macromolecule from Homo sapiens)
- Ttll6 bound to unmodified human microtubule (100 kDa, Complex)
- Tubulin polyglutamylase ttll6 in complex with unmodified human microtubule (Complex from Mus musculus)
- Alpha1b and betai/betaivb microtubule (Complex from Homo sapiens)
- Tubulin beta chain (Macromolecule from Homo sapiens)
- Tubulin polyglutamylase ttll6 (Macromolecule from Mus musculus)