Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8f0g
Q-score: 0.469
Hastie KM, Yu X, Ana-Sosa-Batiz F, Zyla DS, Harkins SS, Hariharan C, Wasserman H, Zandonatti MA, Miller R, Maule E, Kim K, Valentine KM, Shresta S, Saphire EO
Cell Rep (2023) 42 pp. 112421-112421 [ Pubmed: 37083327 DOI: doi:10.1016/j.celrep.2023.112421 ]
- Antibody 1c3 fab light chain (11 kDa, Protein from Homo sapiens)
- Structure of sars-cov-2 omicron ba.1 spike in complex with antibody 1c3 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Antibody 1c3 fab heavy chain,antibody 1c3 fab light chain (Complex from Homo sapiens)
- Antibody 1c3 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (134 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8f0h
Q-score: 0.484
Hastie KM, Yu X, Ana-Sosa-Batiz F, Zyla DS, Harkins SS, Hariharan C, Wasserman H, Zandonatti MA, Miller R, Maule E, Kim K, Valentine KM, Shresta S, Saphire EO
Cell Rep (2023) 42 pp. 112421-112421 [ Pubmed: 37083327 DOI: doi:10.1016/j.celrep.2023.112421 ]
- Antibody fab 1h2 heavy chain, antibody fab 1h2 light chain, antibody fab 2a10 heavy chain, antibody fab 2a10 light chain (Complex from Homo sapiens)
- Antibody fab 1h2 heavy chain (13 kDa, Protein from Homo sapiens)
- Antibody fab 1h2 light chain (10 kDa, Protein from Homo sapiens)
- Structure of sars-cov-2 d614g spike in complex with antibody fabs 1h2 and 2a10 (Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Antibody fab 2a10 heavy chain (12 kDa, Protein from Homo sapiens)
- Spike glycoprotein (134 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody fab 2a10 light chain (11 kDa, Protein from Homo sapiens)
Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8dmh
Q-score: 0.515
Moon-Walker A, Zhang Z, Zyla DS, Buck TK, Li H, Diaz Avalos R, Schendel SL, Hastie KM, Crotty S, Saphire EO
Cell Chem Biol (2023) 30 pp. 403-411.e4 [ Pubmed: 36990092 DOI: doi:10.1016/j.chembiol.2023.03.005 ]
- Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody m28 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glycoprotein g1 (25 kDa, Protein from Lymphocytic choriomeningitis virus)
- 18.5c-m28 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Glycoprotein (Complex from Lymphocytic choriomeningitis mammarenavirus)
- Glycoprotein g2,cobalamin adenosyltransferase-like domain-containing protein trimerization tag (42 kDa, Protein from Lymphocytic choriomeningitis virus)
- 18.5c-m28 fab light chain (23 kDa, Protein from Homo sapiens)
- 18.5c-m28 fab light chain, 18.5c-m28 fab heavy chain (Complex from Homo sapiens)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7t3m
Q-score: 0.505
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
- Spike glycoprotein (127 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody 2-7 scfv (30 kDa, Protein from Escherichia coli)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars cov-2 s, spike glycoprotein, variant d614g with antibody 2-7 scfv (Complex)
SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7t67
Q-score: 0.399
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
Structure of Lassa Virus glycoprotein (Josiah) bound to Fab 25.10C
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7tyv
Q-score: 0.447
Enriquez AS, Buck TK, Li H, Norris MJ, Moon-Walker A, Zandonatti MA, Harkins SS, Robinson JE, Branco LM, Garry RF, Saphire EO, Hastie KM
Cell Rep (2022) 39 pp. 110841-110841 [ Pubmed: 35613585 DOI: doi:10.1016/j.celrep.2022.110841 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lassa virus glycoprotein josiah (Complex from Lassa virus)
- Lassa virus josiah gp complexed with anti-lassa virus antibody fab fragment 25.10c (350 kDa, Complex)
- 25.10c fab fragment (Complex from Homo sapiens)
- 25.10c fab heavy chain (24 kDa, Protein from Homo sapiens)
- Glycoprotein g1 (29 kDa, Protein from Lassa virus)
- 25.10c fab light chain (25 kDa, Protein from Homo sapiens)
- Glycoprotein g2 (19 kDa, Protein from Lassa virus)
EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs
Resolution: 4.12 Å
EM Method: Single-particle
Fitted PDBs: 6pci
Q-score: 0.38
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe Jr JE
Immunity (2020) 52 pp. 388-403.e12 [ DOI: doi:10.1016/j.immuni.2020.01.001 Pubmed: 32023489 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ebola virus (makona) gp (Complex)
- Rebov-520 fab (Complex)
- Rebov-520 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein,virion spike glycoprotein,ebola virus (makona) gp2 (22 kDa, Protein from Ebola virus)
- Rebov-548 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein (31 kDa, Protein from Ebola virus)
- Rebov-520 fab light chain (23 kDa, Protein from Homo sapiens)
- Rebov-548 fab light chain (23 kDa, Protein from Homo sapiens)
- Ebov gpdmuc (makona) in complex with rebov-520 and rebov-548 fabs (450 kDa, Complex from Homo sapiens)
- Rebov-548 fab (Complex)