SARS-CoV-2 VFLIP spike boung to 2 Ab12 Fab fragments
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ Pubmed: 36192374 DOI: doi:10.1038/s41467-022-33030-4 ]
EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs
Resolution: 4.12 Å
EM Method: Single-particle
Fitted PDBs: 6pci
Q-score: 0.38
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe Jr JE
Immunity (2020) 52 pp. 388-403.e12 [ Pubmed: 32023489 DOI: doi:10.1016/j.immuni.2020.01.001 ]
- Virion spike glycoprotein,virion spike glycoprotein,ebola virus (makona) gp2 (22 kDa, Protein from Ebola virus)
- Rebov-520 fab (Complex)
- Ebov gpdmuc (makona) in complex with rebov-520 and rebov-548 fabs (450 kDa, Complex from Homo sapiens)
- Rebov-520 fab light chain (23 kDa, Protein from Homo sapiens)
- Rebov-520 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Ebola virus (makona) gp (Complex)
- Virion spike glycoprotein (31 kDa, Protein from Ebola virus)
- Rebov-548 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Rebov-548 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rebov-548 fab (Complex)
EBOV GP in complex with IgG c2G4 and c13C6 Fabs
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5kel
Q-score: 0.309
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol (2016) 1 pp. 16128-16128 [ Pubmed: 27562261 DOI: doi:10.1038/nmicrobiol.2016.128 ]
- C2g4 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola virus trimeric surface glycoprotein in complex with igg c2g4 and c13c6 fabs (540 kDa, Complex from Zaire ebolavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C2g4 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- C13c6 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- C13c6 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola surface glycoprotein, gp1 (50 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
- Ebola surface glycoprotein, gp2 (16 kDa, Protein from Zaire ebolavirus)
EBOV GP in complex with IgG c4G7 and c13C6 Fabs
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5ken
Q-score: 0.185
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol (2016) 1 pp. 16128-16128 [ Pubmed: 27562261 DOI: doi:10.1038/nmicrobiol.2016.128 ]
- Ebola virus trimeric surface glycoprotein in complex with igg c4g7 and c13c6 fabs (540 kDa, Complex)
- Ebola surface glycoprotein, gp2 (12 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
- C13c6 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- Ebola surface glycoprotein, gp1 (30 kDa, Protein from Zaire ebolavirus)
- C4g7 variable fab domain heavy chain (12 kDa, Protein from Homo sapiens)
- C13c6 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C4g7 variable fab domain light chain (11 kDa, Protein from Homo sapiens)