EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs
Resolution: 4.12 Å
EM Method: Single-particle
Fitted PDBs: 6pci
Q-score: 0.38
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe Jr JE
Immunity (2020) 52 pp. 388-403.e12 [ DOI: doi:10.1016/j.immuni.2020.01.001 Pubmed: 32023489 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ebola virus (makona) gp (Complex)
- Rebov-520 fab (Complex)
- Rebov-520 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein,virion spike glycoprotein,ebola virus (makona) gp2 (22 kDa, Protein from Ebola virus)
- Rebov-548 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein (31 kDa, Protein from Ebola virus)
- Rebov-520 fab light chain (23 kDa, Protein from Homo sapiens)
- Rebov-548 fab light chain (23 kDa, Protein from Homo sapiens)
- Ebov gpdmuc (makona) in complex with rebov-520 and rebov-548 fabs (450 kDa, Complex from Homo sapiens)
- Rebov-548 fab (Complex)
EBOV GPdMuc Makona bound to rEBOV-548 Fab
Resolution: 3.96 Å
EM Method: Single-particle
Fitted PDBs: 6uye
Q-score: 0.413
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe Jr JE
Immunity (2020) 52 pp. 388-403.e12 [ DOI: doi:10.1016/j.immuni.2020.01.001 Pubmed: 32023489 ]
- Ebola virus, mucin deleted, strain makona (Complex from Ebola virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sgp (29 kDa, Protein from Ebola virus)
- Antibody rebov-548 fab, light chain (11 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein (10 kDa, Protein from Ebola virus)
- Rebov-548 fab (Complex from Homo sapiens)
- Antibody rebov-548 fab, heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of ebola virus, mucin deleted, strain makona in complex with rebov-548 fab (Complex)
Ebola virus nucleoprotein - RNA complex
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6nut
Q-score: 0.516
Kirchdoerfer RN, Saphire EO, Ward AB
Acta Crystallogr F Struct Biol Commun (2019) 75 pp. 340-347 [ Pubmed: 31045563 DOI: doi:10.1107/S2053230X19004424 ]
- Ebola virus nucleoprotein bound to rna (177 MDa, Complex from Ebola virus - Mayinga, Zaire, 1976)
- Rna (5'-r(p*ap*ap*ap*ap*ap*a)-3') (1 kDa, RNA from Homo sapiens)
- Nucleoprotein (50 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
EBOV GP in complex with IgG c2G4 and c13C6 Fabs
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5kel
Q-score: 0.309
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol (2016) 1 pp. 16128-16128 [ DOI: doi:10.1038/nmicrobiol.2016.128 Pubmed: 27562261 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C13c6 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- C2g4 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola surface glycoprotein, gp2 (16 kDa, Protein from Zaire ebolavirus)
- Ebola surface glycoprotein, gp1 (50 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
- Ebola virus trimeric surface glycoprotein in complex with igg c2g4 and c13c6 fabs (540 kDa, Complex from Zaire ebolavirus)
- C13c6 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- C2g4 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
EBOV sGP in complex with IgG c13C6 and BDBV91 Fabs
Resolution: 5.5 Å
EM Method: Single-particle
Fitted PDBs: 5kem
Q-score: 0.217
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol (2016) 1 pp. 16128-16128 [ DOI: doi:10.1038/nmicrobiol.2016.128 Pubmed: 27562261 ]
- C13c6 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola virus dimeric secreted glycoprotein in complex with igg c13c6 and bdbv91 fabs (270 kDa, Complex from Zaire ebolavirus)
- Bdbv91 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola secreted glycoprotein (25 kDa, Protein from Zaire ebolavirus)
- C13c6 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- Bdbv91 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
EBOV GP in complex with IgG c4G7 and c13C6 Fabs
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5ken
Q-score: 0.185
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB
Nat Microbiol (2016) 1 pp. 16128-16128 [ DOI: doi:10.1038/nmicrobiol.2016.128 Pubmed: 27562261 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C13c6 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- Ebola surface glycoprotein, gp1 (30 kDa, Protein from Zaire ebolavirus)
- C4g7 variable fab domain light chain (11 kDa, Protein from Homo sapiens)
- C4g7 variable fab domain heavy chain (12 kDa, Protein from Homo sapiens)
- Ebola surface glycoprotein, gp2 (12 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
- C13c6 variable fab domain heavy chain (13 kDa, Protein from Homo sapiens)
- Ebola virus trimeric surface glycoprotein in complex with igg c4g7 and c13c6 fabs (540 kDa, Complex)