Cryo-EM structure of HIV-1 Env(CH848 10.17 DS.SOSIP_DT) in complex with DH1030.1 Fab
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 8dow
Q-score: 0.387
Gobeil SM, Janowska K, Stalls V, Mansouri K, Henderson RC, Edwards RJ, Wiehe K, Saunders K, Acharya P, Williams W, Haynes BF
To Be Published
- Envelope glycoprotein gp120 (51 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dh1030.1 fab light chain (24 kDa, Protein from Macaca mulatta)
- Dh1030.1 fab heavy chain (24 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (18 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env(ch848 10.17 ds.sosip_dt) in complex with dh1030.1 fab (Complex from Macaca mulatta)
Cryo-EM structure of HIV-1 Env(BG505.T332N SOSIP) in complex with DH1030.1 Fab
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8dp1
Q-score: 0.433
Gobeil SM, Janowska K, Stalls V, Mansouri K, Edwards RJ, Henderson RC, Wiehe K, Saunders K, Acharya P, Williams W, Haynes BF
To Be Published
- Envelope glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dh1030.1 fab heavy chain (24 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Dh1030.1 fab light chain (24 kDa, Protein from Macaca mulatta)
- Hiv-1 env(bg505.t332n sosip) in complex with dh1030.1 fab (Complex from Macaca mulatta)
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 8csa
Q-score: 0.33
Gobeil SM-C, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders K, Edwards RJ, Korber B, Haynes BF, Henderson RC, Acharya P
Science (2021) [ DOI: doi:10.1126/science.abi6226 ]
Structure of Alternanthera Mosaic VLP by cryoEM
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7og6
Q-score: 0.492
Thuenemann EC, Byrne MJ, Peyret H, Saunders K, Castells-Graells R, Ferriol I, Santoni M, Steele JFC, Ranson NA, Avesani L, Lopez-Moya JJ, Lomonossoff GP
Viruses (2021) 13 [ Pubmed: 34064959 DOI: doi:10.3390/v13050885 ]
- Rna (5'-r(p*up*up*up*up*u)-3') (1 kDa, RNA from Alternanthera mosaic virus)
- Alternanthera mosaic virus (Virus from Alternanthera mosaic virus)
- Coat protein (22 kDa, Protein from Alternanthera mosaic virus)
UK (B.1.1.7) SARS-CoV-2 S-GSAS-D614G variant spike protein in the 3-RBD-down conformation
Resolution: 3.22 Å
EM Method: Single-particle
Fitted PDBs: 7lws
Q-score: 0.473
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Saunders K, Edwards RJ, Haynes BF, Henderson RC, Acharya P
bioRxiv (2021) [ Pubmed: 33758838 DOI: doi:10.1101/2021.03.11.435037 ]
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer - asymmetric refinement
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 7m0j
Q-score: 0.417
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Saunders K, Edwards RJ, Haynes BF, Henderson RC, Acharya P
bioRxiv (2021) [ Pubmed: 33758838 DOI: doi:10.1101/2021.03.11.435037 ]
Negative stain electron microscopy reconstruction of rS2d-hexapro SARS-CoV-2 spike ectodomain
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Gobeil SMC, Janowska K, Li D, Lu X, Deyton M, Sprenz J, Williams W, Saunders K, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P
bioRxiv (2020) [ Pubmed: 32699852 DOI: doi:10.1101/2020.07.12.199588 ]
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Gobeil SMC, Janowska K, Li D, Lu X, Deyton M, Sprenz J, Williams W, Saunders K, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P
bioRxiv (2020) [ Pubmed: 32699852 DOI: doi:10.1101/2020.07.12.199588 ]
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Gobeil SMC, Janowska K, Li D, Lu X, Deyton M, Sprenz J, Williams W, Saunders K, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P
bioRxiv (2020) [ Pubmed: 32699852 DOI: doi:10.1101/2020.07.12.199588 ]
CryoEM structure of Ageratum Yellow Vein virus (AYVV)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6f2s
Q-score: 0.416
Hesketh EL, Saunders K, Fisher C, Potze J, Stanley J, Lomonossoff GP, Ranson NA
Nat Commun (2018) 9 pp. 2369-2369 [ Pubmed: 29915210 DOI: doi:10.1038/s41467-018-04793-6 ]
- Ageratum yellow vein virus (251 kDa, Virus from Ageratum yellow vein virus)
- Ssdna loop associated with subunit h (1 kDa, DNA from Ageratum yellow vein virus)
- Coat protein subunit i (23 kDa, Protein from Ageratum yellow vein virus)
- Coat protein subunit h (25 kDa, Protein from Ageratum yellow vein virus)
- Capsid protein (22 kDa, Protein from Ageratum yellow vein virus)
- Ssdna loop (2 kDa, DNA from Ageratum yellow vein virus)