BG505 SOSIP.v5.2.N241.N289 in complex with rhesus macaque Fab RM19R
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6vkn
Q-score: 0.452
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, Menis S, Alter G, Schief WR, Crotty S, King NP, Baker D, Silvestri G, Ward AB, Irvine DJ
NPJ Vaccines (2020) 5 pp. 72-72 [ Pubmed: 32802411 DOI: doi:10.1038/s41541-020-00223-1 ]
- Bg505 sosip.v5.2.n241.n289 in complex with rhesus macaque fab rm19r (Complex from Human immunodeficiency virus 1)
- Bg505 sosipv5.2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rm19r heavy chain (13 kDa, Protein from Macaca mulatta)
- Rm19r kappa light chain (11 kDa, Protein from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6vl5
Q-score: 0.333
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, Menis S, Alter G, Schief WR, Crotty S, King NP, Baker D, Silvestri G, Ward AB, Irvine DJ
NPJ Vaccines (2020) 5 pp. 72-72 [ Pubmed: 32802411 DOI: doi:10.1038/s41541-020-00223-1 ]
- Bg505 sosip.v5.2(7s) - gp41 (18 kDa, Protein from synthetic construct)
- Bg505 sosip trimer reconstructed from a designed tetrahedral nanoparticle bg505 sosip-t33_dn2 (Complex from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from synthetic construct)
De novo designed tetrahedral nanoparticle T33_dn2 presenting BG505 SOSIP trimers
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6vl6
Q-score: 0.252
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, Menis S, Alter G, Schief WR, Crotty S, King NP, Baker D, Silvestri G, Ward AB, Irvine DJ
NPJ Vaccines (2020) 5 pp. 72-72 [ Pubmed: 32802411 DOI: doi:10.1038/s41541-020-00223-1 ]
- T33_dn2a (14 kDa, Protein from synthetic construct)
- T33_dn2b (14 kDa, Protein from synthetic construct)
- De novo designed tetrahedral nanoparticle bg505 sosip-t33_dn2 (Complex from synthetic construct)
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Negative Stain EM map of polyclonal serum in complex with BG505 SOSIP.664 from non-human primate RCn
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S
Cell (2019) 177 pp. 1153-1171.e28 [ Pubmed: 31080066 DOI: doi:10.1016/j.cell.2019.04.012 ]