Resolution: 3.77 Å
EM Method: Single-particle
Fitted PDBs: 8dtk
Q-score: 0.437
Malewana RD, Stalls V, May A, Lu X, Martinez DR, Schafer A, Li D, Barr M, Sutherland LL, Lee E, Parks R, Beck WE, Newman A, Bock KW, Minai M, Nagata BM, DeMarco CT, Denny TN, Oguin 3rd TH, Rountree W, Wang Y, Mansouri K, Edwards RJ, Sempowski GD, Eaton A, Muramatsu H, Henderson R, Tam Y, Barbosa C, Tang J, Cain DW, Santra S, Moore IN, Andersen H, Lewis MG, Golding H, Seder R, Khurana S, Montefiori DC, Pardi N, Weissman D, Baric RS, Acharya P, Haynes BF, Saunders KO
bioRxiv (2023) [ Pubmed: 38187726 DOI: doi:10.1101/2023.12.18.572191 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Dh1047 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Dh1047 fab light chain (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rbd directed antibody dh1047 in complex with sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
H1 Solomon Islands 2006 hemagglutinin in complex with Ab111
Caradonna TM, Ronsard L, Yousif AS, Windsor IW, Hecht R, Bracamonte-Moreno T, Roffler AA, Maron MJ, Maurer DP, Feldman J, Marchiori E, Barnes RM, Rohrer D, Lonberg N, Sempowski GD, Kepler TB, Kuraoka M, Lingwood D, Schmidt AG
Cell Rep (2022) 41 pp. 111628-111628 [ DOI: doi:10.1016/j.celrep.2022.111628 Pubmed: 36351401 ]
H1 Solomon Islands 2006 hemagglutinin in complex with Ab109
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 7umm
Q-score: 0.51
Caradonna TM, Ronsard L, Yousif AS, Windsor IW, Hecht R, Bracamonte-Moreno T, Roffler AA, Maron MJ, Maurer DP, Feldman J, Marchiori E, Barnes RM, Rohrer D, Lonberg N, Oguin 3rd TH, Sempowski GD, Kepler TB, Kuraoka M, Lingwood D, Schmidt AG
Cell Rep (2022) 41 pp. 111628-111628 [ DOI: doi:10.1016/j.celrep.2022.111628 Pubmed: 36351401 ]
- Ab109 fab heavy chain, ab 109 fab light chain (Complex from Mus musculus)
- Ab109 fab light chain (23 kDa, Protein from Mus musculus)
- Hemagglutinin (Complex from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (58 kDa, Protein from Influenza A virus (A/Solomon Islands/3/2006(H1N1)))
- Ab109 fab heavy chain (23 kDa, Protein from Mus musculus)
- Hemagglutinin h1 solomon islands/03/2006 in complex with ab109 fab (Complex)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7upw
Q-score: 0.464
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7upx
Q-score: 0.513
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (local refinement of the rbd and fab variable domains) (6 MDa, Complex)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7upy
Q-score: 0.384
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- One rbd-up state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Sp1-77 antibody fab light chain (Protein from Mus musculus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 antibody fab heavy chain (Protein from Mus musculus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Complex of sars-cov2 2p spike with sp1-77 antibody fab (48 kDa, Complex)
- Sp1-77 antibody fab light chain, sp1-77 antibody fab heavy chain (Complex from Mus musculus)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Complex of sars-cov2 2p spike with vhh7-7-53 antibody fab (48 kDa, Complex)
- Vhh7-7-53 antibody fab light chain, vhh7-7-53 antibody fab heavy chain (Complex from Mus musculus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Vhh7-7-53 antibody heavy chain (Protein from Mus musculus)
- Vhh7-7-53 antibody light chain (Protein from Mus musculus)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Complex of sars-cov2 2p spike with vhh7-5-82 antibody fab (48 kDa, Complex)
- Vhh7-5-82 antibody fab light chain (Protein from Mus musculus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Vhh7-5-82 antibody fab heavy chain (Protein from Mus musculus)
- Vhh7-5-82 antibody fab light chain, vhh7-5-82 antibody fab heavy chain (Complex from Mus musculus)
Gobeil SM, Henderson R, Stalls V, Janowska K, Huang X, May A, Speakman M, Beaudoin E, Manne K, Li D, Parks R, Barr M, Deyton M, Martin M, Mansouri K, Edwards RJ, Sempowski GD, Saunders KO, Wiehe K, Williams W, Korber B, Haynes BF, Acharya P
bioRxiv (2022) [ DOI: doi:10.1101/2022.01.25.477784 Pubmed: 35118469 ]