Electron Microscopy Data Bank

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Cryo-EM structure of the sarilumab Fab/IL-6R complex

Release date: March 20, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iow
Q-score: 0.497

Wang M, Chen L, He J, Xia W, Ye Z, She J

Cell Rep (2024) 43 pp. 113819-113819 [ Pubmed: 38393945 DOI: doi:10.1016/j.celrep.2024.113819 ]

Sample:

Interleukin-6 receptor subunit alpha (40 kDa, Protein from Homo sapiens)
The sarilumab fab/il-6r complex (Complex from Homo sapiens)
Light chain of sarilumab fab (23 kDa, Protein from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Heavy chain of sarilumab fab (23 kDa, Protein from Homo sapiens)

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EMD-35048

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Structure of the human CLC-7/Ostm1 complex reveals a novel state

Release date: Jan. 3, 2024
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8hvt
Q-score: 0.498

Zhang ZX, Chen L, He J, She J

JUSTC (2023) 53 [ DOI: doi:10.52396/JUSTC-2022-0172 ]

Sample:

Osteopetrosis-associated transmembrane protein 1 (37 kDa, Protein from Homo sapiens)
Clc-7/ostm1 (Complex from Homo sapiens)
2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
H(+)/cl(-) exchange transporter 7 (88 kDa, Protein from Homo sapiens)

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EMD-34087

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The cargo delivery vehicle Hcp-VgrG-PAAR of the Type VI secretion system

Release date: Aug. 30, 2023
Resolution: 2.8 Å
EM Method: Single-particle

He W, Wu K, Ouyang Z, Bai Y, Luo W, Wu D, An H, Guo Y, Jiao M, Qin Q, Zhang J, Wu Y, She J, Hwang PM, Zheng F, Zhu L, Wen Y

Cell Rep (2023) 42 pp. 112781-112781 [ Pubmed: 37421630 DOI: doi:10.1016/j.celrep.2023.112781 ]

Sample:

Hcp-vgrg-paar of the type vi secretion system (Complex from Bacteroides fragilis)

EMD-34094

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Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter

Release date: May 3, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7ytw
Q-score: 0.507

Wang M, He J, Li S, Cai Q, Zhang K, She J

Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]

Sample:

Water (18 Da, Ligand)
Svct1 (Complex from Mus musculus)
Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)
Sodium ion (22 Da, Ligand)
Ascorbic acid (176 Da, Ligand)

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EMD-34095

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Mouse SVCT1 in an apo state

Release date: May 3, 2023
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7yty
Q-score: 0.447

Wang M, He J, Li S, Cai Q, Zhang K, She J

Nat Commun (2023) 14 pp. 1361-1361 [ Pubmed: 36914666 DOI: doi:10.1038/s41467-023-37037-3 ]

Sample:

Svct1 (Complex from Mus musculus)
Solute carrier family 23 member 1 (65 kDa, Protein from Mus musculus)

EMD-33088

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Structure of Arabidopsis thaliana CLCa

Release date: March 22, 2023
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 7xa9
Q-score: 0.583

He J, Wang M, Li S, Chen L, Zhang K, She J

J Biol Chem (2023) 299 pp. 102833-102833 [ DOI: doi:10.1016/j.jbc.2022.102833 Pubmed: 36581207 ]

Sample:

Atclca (Complex from Arabidopsis thaliana)
Magnesium ion (24 Da, Ligand)
Adenosine-5'-triphosphate (507 Da, Ligand)
Chloride channel protein clc-a (88 kDa, Protein from Arabidopsis thaliana)
Nitrate ion (62 Da, Ligand)

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