Electron Microscopy Data Bank

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The cargo delivery vehicle Hcp-VgrG-PAAR of the Type VI secretion system

Release date: Aug. 30, 2023
Resolution: 2.8 Å
EM Method: Single-particle

He W, Wu K, Ouyang Z, Bai Y, Luo W, Wu D, An H, Guo Y, Jiao M, Qin Q, Zhang J, Wu Y, She J, Hwang PM, Zheng F, Zhu L, Wen Y

Cell Rep (2023) 42 pp. 112781-112781 [ Pubmed: 37421630 DOI: doi:10.1016/j.celrep.2023.112781 ]

Sample:

Hcp-vgrg-paar of the type vi secretion system (Complex from Bacteroides fragilis)

EMD-30929

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The negatively stained reconstruction of cytoplasmic AdeS in APO state

Release date: June 23, 2021
Resolution: 26.0 Å
EM Method: Single-particle

Ouyang Z, Zheng F, Zhu L, Felix J, Wu D, Wu K, Gutsche I, Wu Y, Hwang PM, She J, Wen Y

iScience (2021) 24 pp. 102476-102476 [ DOI: doi:10.1016/j.isci.2021.102476 Pubmed: 34113820 ]

Sample:

Histidine kinase ades in apo state (Complex from Acinetobacter baumannii)

EMD-30930

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The negatively stained reconstruction of cytoplasmic AdeS in ATP-bound state

Release date: June 23, 2021
Resolution: 22.0 Å
EM Method: Single-particle

Ouyang Z, Zheng F, Zhu L, Felix J, Wu D, Wu K, Gutsche I, Wu Y, Hwang PM, She J, Wen Y

iScience (2021) 24 pp. 102476-102476 [ DOI: doi:10.1016/j.isci.2021.102476 Pubmed: 34113820 ]

Sample:

Histidine kinase ades in atp-bound state (Complex from Acinetobacter baumannii)

EMD-22213

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Calcium channel

Release date: Sept. 9, 2020
Resolution: 4.5 Å
EM Method: Single-particle

Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y

eLife (2020) 9 [ DOI: doi:10.7554/eLife.60513 Pubmed: 32762847 ]

Sample:

Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)

EMD-22214

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Calcium channel

Release date: Sept. 9, 2020
Resolution: 7.0 Å
EM Method: Single-particle

Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y

eLife (2020) 9 [ DOI: doi:10.7554/eLife.60513 Pubmed: 32762847 ]

Sample:

Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)

EMD-22215

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MCU holocomplex in High-calcium state

Release date: Sept. 9, 2020
Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 6xjv
Q-score: 0.31

Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y

eLife (2020) 9 [ DOI: doi:10.7554/eLife.60513 Pubmed: 32762847 ]

Sample:

Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Calcium uptake protein 2, mitochondrial (49 kDa, Protein from Homo sapiens)

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EMD-22216

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MCU holocomplex in Low-calcium blocking state

Release date: Sept. 9, 2020
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6xjx
Q-score: 0.308

Wang Y, Han Y, She J, Nguyen NX, Mootha VK, Bai XC, Jiang Y

eLife (2020) 9 [ DOI: doi:10.7554/eLife.60513 Pubmed: 32762847 ]

Sample:

Mcu/emre/micu1/micu2 complex (529 kDa, Complex from Homo sapiens)
Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Calcium uptake protein 2, mitochondrial (49 kDa, Protein from Homo sapiens)

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EMD-0625

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Human MCU-EMRE complex, dimer of channel

Release date: May 22, 2019
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6o58
Q-score: 0.381

Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y

Cell (2019) 177 pp. 1252- [ DOI: doi:10.1016/j.cell.2019.03.050 Pubmed: 31080062 ]

Sample:

Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
Mcu/emre complex (Complex from Homo sapiens)
Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Calcium ion (40 Da, Ligand)

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EMD-0626

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Human MCU-EMRE complex, monomer of channel

Release date: May 22, 2019
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6o5b
Q-score: 0.447

Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y

Cell (2019) 177 pp. 1252- [ DOI: doi:10.1016/j.cell.2019.03.050 Pubmed: 31080062 ]

Sample:

Essential mcu regulator, mitochondrial (11 kDa, Protein from Homo sapiens)
Mcu/emre complex (Complex from Homo sapiens)
Calcium uniporter protein, mitochondrial (39 kDa, Protein from Homo sapiens)
Calcium ion (40 Da, Ligand)

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EMD-0627

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Cryo-EM map of human MCU

Release date: May 22, 2019
Resolution: 7.7 Å
EM Method: Single-particle

Wang Y, Nguyen NX, She J, Zeng W, Yang Y, Bai XC, Jiang Y

Cell (2019) 177 pp. 1252-1261.e13 [ DOI: doi:10.1016/j.cell.2019.03.050 Pubmed: 31080062 ]

Sample:

Mcu (Protein from Homo sapiens)
Mcu (Complex from Homo sapiens)

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