HIV-1 BaL Env in complex with CD4 mimetic CJF-III-288 and 17b IgG
Richard J, Grunst MW, Niu L, Diaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M, Gottumukkala S, Li W, Dionne K, Belanger E, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D, Smith 3rd AB, Mothes W, Munro JB, Pazgier M, Finzi A
bioRxiv (2024) [ DOI: doi:10.1101/2024.08.27.609961 Pubmed: 39253431 ]
Cryo-EM structure of BG505 SOSIP trimer purified via Galanthus nivalis lectin chromatography
Parthasarathy D, Pothula KR, Ratnapriya S, Cervera Benet H, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sodroski J, Acharya P, Herschhorn A
Nat Commun (2024) 15 pp. 7334-7334 [ Pubmed: 39187497 DOI: doi:10.1038/s41467-024-51656-4 ]
Cryo-EM structure of 1059 SOSIP trimer purified via Galanthus nivalis lectin chromatography
Parthasarathy D, Pothula KR, Ratnapriya S, Cervera Benet H, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sodroski J, Acharya P, Herschhorn A
Nat Commun (2024) 15 pp. 7334-7334 [ Pubmed: 39187497 DOI: doi:10.1038/s41467-024-51656-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1059 sosip surface protein gp120 (55 kDa, Protein from Human immunodeficiency virus 1)
- Cryo-em structure of 1059 sosip trimer purified via galanthus nivalis lectin chromatography (217 kDa, Complex from Human immunodeficiency virus 1)
- 1059 sosip transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8fad
Q-score: 0.332
Wang K, Zhang S, Go EP, Ding H, Wang WL, Nguyen HT, Kappes JC, Desaire H, Sodroski J, Mao Y
Commun Biol (2023) 6 pp. 535-535 [ DOI: doi:10.1038/s42003-023-04916-w Pubmed: 37202420 ]
- Transmembrane protein gp41 (15 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env ad8 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1-[(2r)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione (406 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8fae
Q-score: 0.333
Wang K, Zhang S, Go EP, Ding H, Wang WL, Nguyen HT, Kappes JC, Desaire H, Sodroski J, Mao Y
Commun Biol (2023) 6 pp. 535-535 [ DOI: doi:10.1038/s42003-023-04916-w Pubmed: 37202420 ]
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hiv-1 env ae2.1 (Complex from Human immunodeficiency virus 1)
- 1-[(2r)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione (406 Da, Ligand)
CryoEM structure of SARS-CoV-2 HexaPro spike in complex with S2-binding CV3-25
Li W, Chen Y, Prevost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vezina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Cote M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W
Cell Rep (2022) 38 pp. 110210-110210 [ DOI: doi:10.1016/j.celrep.2021.110210 Pubmed: 34971573 ]
- Sars-cov-2 s-6p in complex with cv3-25 (600 kDa, Complex from Homo sapiens)
- Sars-cov-2 hexapro-spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Cv3-25 heavy chain (Protein from Homo sapiens)
- Cv3-25 light chain (Protein from Homo sapiens)
Asymmetric structures of the uncleaved full-length HIV-1 envelope glycoprotein trimer
Subtomogram averaging of SARS-CoV-2 Spike Protein bound to CV3-1
Li W, Chen Y, Prevost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vezina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Cote M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W
Cell Rep (2022) 38 pp. 110210-110210 [ DOI: doi:10.1016/j.celrep.2021.110210 Pubmed: 34971573 ]
Subtomogram averaging of SARS-CoV-2 Spike Protein bound to Fab CV3-25
Li W, Chen Y, Prevost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vezina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Cote M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W
Cell Rep (2022) 38 pp. 110210-110210 [ DOI: doi:10.1016/j.celrep.2021.110210 Pubmed: 34971573 ]