Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yfq
Q-score: 0.435
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ Pubmed: 38658622 DOI: doi:10.1038/s41594-024-01287-6 ]
- Rna (Complex)
- Rna (5'-r(*up*cp*cp*ap*up*gp*up*up*gp*ap*up*gp*gp*up*ap*a)-3') (5 kDa, RNA from Homo sapiens)
- Efpiwi(n959k) (Complex from Ephydatia fluviatilis)
- Piwi (92 kDa, Protein from Ephydatia fluviatilis)
- Efpiwi(n959k)-pirna-16nt target (Complex)
- Magnesium ion (24 Da, Ligand)
- Pirna (7 kDa, RNA from Homo sapiens)
Cryo-EM structure of Hili in complex with piRNA
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfx
Q-score: 0.425
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Pirna (8 kDa, RNA from Homo sapiens)
- Hili-pirna (Complex)
- Piwi-like protein 2 (114 kDa, Protein from Homo sapiens)
- Hili (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Pirna (Complex)
Cryo-EM structure of the Mili-piRNA- target ternary complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfy
Q-score: 0.406
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01287-6 Pubmed: 38658622 ]
- Pirna (8 kDa, RNA from Homo sapiens)
- Piwi-like protein 2 (91 kDa, Protein from Mus musculus)
- Rna (5'-r(p*cp*cp*ap*up*gp*up*up*gp*ap*up*gp*gp*up*ap*a)-3') (4 kDa, RNA from Homo sapiens)
- Mili-pirna-15nt target (Complex)
- Magnesium ion (24 Da, Ligand)
- Mili (Complex from Mus musculus)
- Rna (Complex)
Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7yg6
Q-score: 0.399
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ Pubmed: 38658622 DOI: doi:10.1038/s41594-024-01287-6 ]
- Efpiwi(n959k) (Complex from Ephydatia fluviatilis)
- Piwi (92 kDa, Protein from Ephydatia fluviatilis)
- Magnesium ion (24 Da, Ligand)
- Pirna (Complex)
- Pirna (7 kDa, RNA from Homo sapiens)
- Efpiwi(n959k)-pirna (Complex)
Cryo-EM structure of the Mili in complex with piRNA
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7ygn
Q-score: 0.5
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S, Zhang Z, Song CQ, Wu J, Shen EZ
Nat Struct Mol Biol (2024) [ Pubmed: 38658622 DOI: doi:10.1038/s41594-024-01287-6 ]
- Piwi-like protein 2 (91 kDa, Protein from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Pirna (Complex)
- Mili-pirna (Complex)
- Mili (Complex from Mus musculus)
- Pirna (8 kDa, RNA from Homo sapiens)