ASFV RNAP M1249L C-tail occupied complex4 (MCOC4)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Magnesium ion (24 Da, Ligand)
- D339l (38 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- M1249l (144 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- C147l (16 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (140 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex4 (mcoc4) (Complex from African swine fever virus)
- Dna-directed rna polymerase subunit (163 kDa, Protein from African swine fever virus)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase subunit beta (138 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- D339l (9 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*tp*tp*cp*gp*cp*cp*gp*tp*tp*gp*cp*gp*tp*ap*tp*tp*tp*gp*tp*gp*tp*ap*g)-3') (7 kDa, DNA from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Rna polymerase subunit 6 (12 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*cp*gp*cp*ap*ap*cp*gp*gp*cp*gp*a)-3') (3 kDa, DNA from African swine fever virus)
- Asfv rnap elongation complex (Complex from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Rna (5'-r(p*cp*up*ap*cp*ap*cp*ap*ap*a)-3') (2 kDa, RNA from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex1 (MCOC1)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8xx5
Q-score: 0.607
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- D339l (38 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Asfv rnap m1249l c-tail occupied complex1 (mcoc1) (Complex from African swine fever virus)
- M1249l (137 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xxp
Q-score: 0.591
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- C147l (11 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- D339l (16 kDa, Protein from African swine fever virus)
- Asfv rnap core complex (Complex from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex2 (MCOC2)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- M1249l (135 kDa, Protein from African swine fever virus)
- D339l (38 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex2 (mcoc2) (Complex from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex3 (MCOC3)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xy6
Q-score: 0.519
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- M1249l (66 kDa, Protein from African swine fever virus)
- C147l (14 kDa, Protein from African swine fever virus)
- D339l (16 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex3 (mcoc3) (Complex from African swine fever virus)
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
EB-bound E46K alpha-synuclein fibrils
Liu K, Tao Y, Zhao Q, Xia W, Li X, Zhang S, Yao Y, Xiang H, Han C, Tan L, Sun B, Li D, Li A, Liu C
PNAS (2024) 121 pp. e2321633121-e2321633121 [ Pubmed: 39172784 DOI: doi:10.1073/pnas.2321633121 ]
- Eb-bound e46k alpha-synuclein fibril (Complex from Homo sapiens)
- 4-azanyl-6-[[4-[4-[(~{e})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid (872 Da, Ligand)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
CR-bound E46K alpha-synuclein fibrils
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8x7m
Q-score: 0.115
PiB-bound E46K mutanted alpha-synuclein fibrils
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8x7o
Q-score: 0.464
Liu K, Tao Y, Zhao Q, Xia W, Li X, Zhang S, Yao Y, Xiang H, Han C, Tan L, Sun B, Li D, Li A, Liu C
PNAS (2024) 121 pp. e2321633121-e2321633121 [ Pubmed: 39172784 DOI: doi:10.1073/pnas.2321633121 ]
- Pib-bound e46k mutated alpha-synuclein fibril (Complex from Homo sapiens)
- 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol (256 Da, Ligand)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)