Structure of PfNT1(Y190A)-GFP in complex with GSK4
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 7ydq
Q-score: 0.31
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7x6l
Q-score: 0.167
Sun X, Liu C, Lu X, Ling Z, Yi C, Zhang Z, Li Z, Jin M, Wang W, Tang S, Wang F, Wang F, Wangmo S, Chen S, Li L, Ma L, Zhang Y, Yang Z, Dong X, Qian Z, Ding J, Wang D, Cong Y, Sun B
Nat Commun (2022) 13 pp. 2378-2378 [ DOI: doi:10.1038/s41467-022-29950-w Pubmed: 35501328 ]
- The light chain of the antibody 12 fab (23 kDa, Protein from Homo sapiens)
- Hemagglutinin (20 kDa, Protein from Influenza A virus)
- Cryo-em structure of h3 hemagglutinin from a/hongkong/01/1968 in complex with a neutralizing antibody 28-12 (Complex from Influenza A virus)
- Hemagglutinin (36 kDa, Protein from Influenza A virus (A/Hong Kong/1/1968(H3N2)))
- Heavy chain of antibody 12 fab (24 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7x6o
Q-score: 0.145
Sun X, Liu C, Lu X, Ling Z, Yi C, Zhang Z, Li Z, Jin M, Wang W, Tang S, Wang F, Wang F, Wangmo S, Chen S, Li L, Ma L, Zhang Y, Yang Z, Dong X, Qian Z, Ding J, Wang D, Cong Y, Sun B
Nat Commun (2022) 13 pp. 2378-2378 [ DOI: doi:10.1038/s41467-022-29950-w Pubmed: 35501328 ]
- Hemagglutinin (37 kDa, Protein from Influenza A virus)
- H1 hemagglutinin from a/washington/05/2011 in complex with a neutralizing antibody 28-12 (Complex from Influenza A virus)
- Hemagglutinin (20 kDa, Protein from Influenza A virus)
- The light chain of antibody 12 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of antibody 12 fab (24 kDa, Protein from Homo sapiens)
cryo-EM of human GLP-1R bound to non-peptide agonist LY3502970
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6xox
Q-score: 0.482
Kawai T, Sun B, Yoshino H, Feng D, Suzuki Y, Fukazawa M, Nagao S, Wainscott DB, Showalter AD, Droz BA, Kobilka TS, Coghlan MP, Willard FS, Kawabe Y, Kobilka BK, Sloop KW
PNAS (2020) 117 pp. 29959-29967 [ DOI: doi:10.1073/pnas.2014879117 Pubmed: 33177239 ]
- Glucagon-like peptide 1 receptor (51 kDa, Protein from Homo sapiens)
- Cryo-em structure of the glucagon-like peptide-1 receptor in complex with g protein and a non-peptide agonist ly3502970 (150 kDa, Complex)
- Glucagon-like peptide 1 receptor (Complex from Homo sapiens)
- Alpha subunit of gs with n-terminus swapped with equivalent residues in gi,guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas (43 kDa, Protein from Homo sapiens)
- Single-chain variable fragment 16 (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Trimeric stimulatory g protein (Complex from Homo sapiens)
- Nanobody 35 (Complex from Lama glama)
- Nanobody 35 (17 kDa, Protein from Lama glama)
- 3-[(1s,2s)-1-(5-[(4s)-2,2-dimethyloxan-4-yl]-2-{(4s)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1h-indazol-5-yl)-2-oxo-2,3-dihydro-1h-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5h-pyrazolo[4,3-c]pyridine-5-carbonyl}-1h-indol-1-yl)-2-methylcyclopropyl]-1,2,4-oxadiazol-5(4h)-one (882 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Single-chain variable fragment scfv16 (27 kDa, Protein from Mus musculus)
Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6vcb
Q-score: 0.452
Bueno AB, Sun B, Willard FS, Feng D, Ho JD, Wainscott DB, Showalter AD, Vieth M, Chen Q, Stutsman C, Chau B, Ficorilli J, Agejas FJ, Cumming GR, Jimenez A, Rojo I, Kobilka TS, Kobilka BK, Sloop KW
Nat Chem Biol (2020) 16 pp. 1105-1110 [ DOI: doi:10.1038/s41589-020-0589-7 Pubmed: 32690941 ]
- Glucagon-like peptide 1 receptor (51 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- 1-[(1r)-1-(2,6-dichloro-3-methoxyphenyl)ethyl]-6-{2-[(2r)-piperidin-2-yl]phenyl}-1h-benzimidazole (480 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Nanobody 35 (Complex from Lama glama)
- Cryo-em structure of the glucagon-like peptide-1 receptor in complex with g protein, glp-1 peptide and a positive allosteric modulator (150 kDa, Complex)
- Glucagon-like peptide 1 receptor, glucagon-like peptide 1 (Complex from Homo sapiens)
- Nanobody 35 (17 kDa, Protein from Lama glama)
- Glucagon-like peptide 1 (3 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (44 kDa, Protein from Homo sapiens)
Apo form metabotropic glutamate receptor 5 with Nanobody 43
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK
Nature (2019) 566 pp. 79-84 [ DOI: doi:10.1038/s41586-019-0881-4 Pubmed: 30675062 ]
- Nanobody 43 (Protein from Lama glama)
- Metabotropic glutamate receptor 5 - nb43 complex (220 kDa, Complex from Homo sapiens)
- Metabotropic glutamate receptor 5 (Protein from Homo sapiens)
Metabotropic Glutamate Receptor 5 bound to L-quisqualate and Nb43
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6n51
Q-score: 0.341
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK
Nature (2019) 566 pp. 79-84 [ DOI: doi:10.1038/s41586-019-0881-4 Pubmed: 30675062 ]
- Nanobody 43 (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Metabotropic glutamate receptor 5 (90 kDa, Protein from Homo sapiens)
- Complex between metabotropic glutamate receptor 5 bound to l-quisqualate and nb43 (220 kDa, Complex from Homo sapiens)
- (s)-2-amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid (189 Da, Ligand)
Metabotropic Glutamate Receptor 5 Apo Form
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6n52
Q-score: 0.312
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK
Nature (2019) 566 pp. 79-84 [ DOI: doi:10.1038/s41586-019-0881-4 Pubmed: 30675062 ]
- Metabotropic glutamate receptor 5 (97 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Metabotropic glutamate receptor 5 in nanodiscs (200 kDa, Complex from Homo sapiens)