Cryo-EM structure of the CHA-bound mTAAR1 complex
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8wcc
Q-score: 0.48
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L, Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, Yan W, Kong Y, Yang L, Wang X, Lei D, Feng X, Liu X, Yu X, Wang Y, Li Q, Shao ZH, Yang F, Sun JP
Cell (2023) 186 pp. 5347-5362.e24 [ Pubmed: 37963465 DOI: doi:10.1016/j.cell.2023.10.014 ]
- Cyclohexylammonium ion (100 Da, Ligand)
- Trace amine-associated receptor 1 (37 kDa, Protein from Mus musculus)
- Cryo-em structure of the cha-bound mtaar1 complex (Complex from Mus musculus)
Cryo-EM structure of the SPE-mTAAR9 complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8iwe
Q-score: 0.493
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP
Nature (2023) 618 pp. 193-200 [ DOI: doi:10.1038/s41586-023-06106-4 Pubmed: 37225986 ]
- Trace amine-associated receptor 9 (38 kDa, Protein from Mus musculus)
- Spermidine (145 Da, Ligand)
- Cryo-em structure of the spe-bound mtaar9 complex (Complex from Mus musculus)
Cryo-EM structure of the PEA-bound mTAAR9 complex
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8iwm
Q-score: 0.491
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP
Nature (2023) 618 pp. 193-200 [ DOI: doi:10.1038/s41586-023-06106-4 Pubmed: 37225986 ]
- Trace amine-associated receptor 9 (38 kDa, Protein from Mus musculus)
- Cryo-em structure of the pea-bound mtaar9 complex (Complex from Mus musculus)
- 2-phenylethylamine (122 Da, Ligand)
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, local
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7vv0
Q-score: 0.469
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, Li Z, Zhou J, Yu X, Gao N, Sun JP
Nature (2021) 600 pp. 164-169 [ DOI: doi:10.1038/s41586-021-04077-y Pubmed: 34789875 ]
- Mas-related g-protein coupled receptor member x2 (37 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Cryo-em structure of pseudoallergen receptor mrgprx2 complex with pamp-12, local (Complex from Homo sapiens)
- Peptide from pro-adrenomedullin (1 kDa, Protein from Homo sapiens)
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with linear cortistatin-14, local
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7vv4
Q-score: 0.471
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, Li Z, Zhou J, Yu X, Gao N, Sun JP
Nature (2021) 600 pp. 164-169 [ DOI: doi:10.1038/s41586-021-04077-y Pubmed: 34789875 ]
- Mas-related g-protein coupled receptor member x2 (37 kDa, Protein from Homo sapiens)
- Cryo-em structure of pseudoallergen receptor mrgprx2 complex with linear cortistatin-14, local (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Circular cortistatin-14 (1 kDa, Protein from Homo sapiens)
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80 (local)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7vv6
Q-score: 0.502
Yang F, Guo L, Li Y, Wang G, Wang J, Zhang C, Fang GX, Chen X, Liu L, Yan X, Liu Q, Qu C, Xu Y, Xiao P, Zhu Z, Li Z, Zhou J, Yu X, Gao N, Sun JP
Nature (2021) 600 pp. 164-169 [ DOI: doi:10.1038/s41586-021-04077-y Pubmed: 34789875 ]
- Cryo-em structure of pseudoallergen receptor mrgprx2 complex with c48/80 (local) (Complex from Homo sapiens)
- Mas-related g-protein coupled receptor member x2 (37 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{n}-methyl-ethanamine (519 Da, Ligand)