Cryo-EM structure of defence-associatedsirtuin 2 (DSR2) H171A protein
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8xew
Q-score: 0.456
Zhang H, Li Y, Li L, Chen L, Zhu C, Sun L, Dong P, Jing D, Yang J, Fu L, Xiao F, Xia N, Li S, Zheng Q, Wu Y
Sci Adv (2024) 10 pp. eadn5691-eadn5691 [ DOI: doi:10.1126/sciadv.adn5691 Pubmed: 39083599 ]
- Dsr2 h171a (Complex from Bacillus sp. DSM 5850)
- Dsr2 h171a (118 kDa, Protein from Bacillus sp. DSM 5850)
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8xfe
Q-score: 0.465
Zhang H, Li Y, Li L, Chen L, Zhu C, Sun L, Dong P, Jing D, Yang J, Fu L, Xiao F, Xia N, Li S, Zheng Q, Wu Y
Sci Adv (2024) 10 pp. eadn5691-eadn5691 [ DOI: doi:10.1126/sciadv.adn5691 Pubmed: 39083599 ]
- Dsr2 protein in complex with dsad1 (Complex)
- Dsr2 h171a (Complex from Bacillus sp. DSM 5850)
- Dsad1 (13 kDa, Protein from Phage #D)
- Dsad1 (Complex from Phage #D)
- Dsr2(h171a) (118 kDa, Protein from Bacillus sp. DSM 5850)
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 8xff
Q-score: 0.442
Zhang H, Li Y, Li L, Chen L, Zhu C, Sun L, Dong P, Jing D, Yang J, Fu L, Xiao F, Xia N, Li S, Zheng Q, Wu Y
Sci Adv (2024) 10 pp. eadn5691-eadn5691 [ DOI: doi:10.1126/sciadv.adn5691 Pubmed: 39083599 ]
- Dsr2 h171a protein in complex with spr phage tail tube (Complex)
- Spr tail tube protein (Complex from Phage #D)
- Dsr2 h171a (Complex from Bacillus sp. DSM 5850)
- Spr tail tube protein (29 kDa, Protein from Phage #D)
- Dsr2(h171a) (118 kDa, Protein from Bacillus sp. DSM 5850)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j2g
Q-score: 0.482
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8svf
Q-score: 0.383
Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ
Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]
- Dna/rna (187-mer) (58 kDa, Macromolecule from synthetic construct)
- Ubiquitin carboxyl-terminal hydrolase bap1 (80 kDa, Protein from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Dna/rna (327-mer) (102 kDa, Macromolecule from synthetic construct)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Histone h2a type 1 (14 kDa, Protein from Xenopus laevis)
- Bap1/asxl1 bound to the h2ak119ub nucleosome (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Polycomb group protein asxl1 (165 kDa, Protein from Homo sapiens)
Map focused on acidic patch BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ
Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]
Overall map of BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
Thomas JF, Valencia-Sanchez MI, Tamburri S, Gloor SL, Rustichelli S, Godinez-Lopez V, De Ioannes P, Lee R, Abini-Agbomson S, Gretarsson K, Burg JM, Hickman AR, Sun L, Gopinath S, Taylor HF, Sun ZW, Ezell RJ, Vaidya A, Meiners MJ, Cheek MA, Rice WJ, Svetlov V, Nudler E, Lu C, Keogh MC, Pasini D, Armache KJ
Sci Adv (2023) 9 pp. eadg9832-eadg9832 [ Pubmed: 37556531 DOI: doi:10.1126/sciadv.adg9832 ]