Tetrameric human mitochondrial Hsp90 (TRAP1) in the presence of AMP-PNP
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7klu
Q-score: 0.451
Liu YX, Agard DA, Elnatan D, Sun M, Larson AG
To Be Published
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Tetrameric human mitochondrial hsp90 (trap1) in the presence of amp-pnp (360 kDa, Complex from Homo sapiens)
- Heat shock protein 75 kda, mitochondrial, spycatcher (87 kDa, Protein from synthetic construct)
- Heat shock protein 75 kda, mitochondrial, spytag, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (chimera) (93 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7klv
Q-score: 0.528
Liu YX, Agard DA, Elnatan D, Sun M, Larson AG
To Be Published
- Full-length human mitochondrial hsp90 (trap1) spycatcher/spytag-sdhb heterodimer in the presence of amp-pnp (180 kDa, Complex from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Heat shock protein 75 kda, mitochondrial, spycatcher (87 kDa, Protein from synthetic construct)
- Heat shock protein 75 kda, mitochondrial, spytag, succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (chimera) (93 kDa, Protein from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) with AMP-PNP
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7kck
Q-score: 0.477
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Human trap1 dimer with amp-pnp (147 kDa, Complex from Homo sapiens)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) in complex with SdhB in the presence of AMP-PNP
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7kcl
Q-score: 0.506
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (15 kDa, Protein from Homo sapiens)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
Full-length human mitochondrial Hsp90 (TRAP1) in complex with SdhB in the presence of AMP-PNP
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7kcm
Q-score: 0.459
Liu YX, Agard DA, Elnatan D, Sun M, Myasnikov AG
To Be Published
- Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (15 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Human trap1 in complex with sdhb in the presence of amp-pnp (162 kDa, Complex from Homo sapiens)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Heat shock protein 75 kda, mitochondrial (74 kDa, Protein from Homo sapiens)
Human Tom70 in complex with SARS CoV2 Orf9b
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7kdt
Q-score: 0.473
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Huttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbolle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss 3rd FR, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech Jr TH, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, Garcia-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ
Science (2020) 370 [ DOI: doi:10.1126/science.abe9403 Pubmed: 33060197 ]
- Orf9b-tom70 complex (Complex from Homo sapiens)
- Orf9b protein (10 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Mitochondrial import receptor subunit tom70 (56 kDa, Protein from Homo sapiens)