p97 (VCP) mutant - F539A state III
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8pqx
Q-score: 0.316
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Tertiary complex of the hexameric p97 f539a mutant (state iii) (530 kDa, Complex from Homo sapiens)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
p97 (VCP) mutant - F539A (ATP)
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
p97 (VCP) mutant - F539A with its adaptor
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8r0e
Q-score: 0.516
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Tertiary complex of the hexameric p97 f266a mutant (530 kDa, Complex from Homo sapiens)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
p97 (VCP) double mutant - F266A F539A
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rs9
Q-score: 0.335
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Tertiary complex of the hexameric p97 f266a f539a double mutant (530 kDa, Complex from Homo sapiens)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
p97 (VCP) mutant - F539A ADP state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8rsb
Q-score: 0.386
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Tertiary complex of the hexameric p97 f539a mutant adp state (530 kDa, Complex from Homo sapiens)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8rsc
Q-score: 0.399
Arie M, Matzov D, Karmona R, Szenkier N, Stanhill A, Navon A
iScience (2024) 27 pp. 110061-110061 [ Pubmed: 38947518 DOI: doi:10.1016/j.isci.2024.110061 ]
- Tertiary complex of the hexameric p97 f539a mutant (530 kDa, Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase (89 kDa, Protein from Homo sapiens)
Bovine 20S proteasome, untreated
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8azk
Q-score: 0.518
Szenkier N, Arie M, Matzov D, Sertchook R, Carmeli R, Cascio P, Stanhill A, Shalev Benami M, Navon A
To Be Published
- Untreated 20s proteasome (700 kDa, Complex from Bos taurus)
- Proteasome subunit alpha type-5 (26 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-6 (21 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-6 (27 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-5 (22 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-1 (29 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-2 (25 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-3 (28 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-7 (25 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-7 (27 kDa, Protein from Bos taurus)
- Proteasome subunit alpha type-4 (29 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-3 (22 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-4 (24 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-1 (23 kDa, Protein from Bos taurus)
- Proteasome subunit beta type-2 (22 kDa, Protein from Bos taurus)
Partially disassembled 20S proteasome upon disulfide bond formation.
Szenkier N, Arie M, Matzov D, Sertchook R, Carmeli R, Cascio P, Stanhill A, Shalev Benami M, Navon A
To Be Published
- Untreated 20s proteasome (700 kDa, Complex from Bos taurus)
A gap across the beta rings in 20S proteasome
Szenkier N, Arie M, Matzov D, Sertchook R, Carmeli R, Cascio P, Stanhill A, Shalev Benami M, Navon A
To Be Published
- Untreated 20s proteasome (700 kDa, Complex from Bos taurus)