RNA polymerase I pre-initiation complex
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5oa1
Q-score: 0.189
Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Muller CW
EMBO J (2017) 36 pp. 2698-2709 [ Pubmed: 28739580 DOI: doi:10.15252/embj.201796958 ]
- Rrn3_yeast rna polymerase i-specific transcription initiation factor rrn3 (Protein from Saccharomyces cerevisiae)
- Rna polymerase i pre-initiation complex with core factor, rrn3 and transcription scaffold (Complex from Saccharomyces cerevisiae)
- Rrn6_yeast rna polymerase i-specific transcription initiation factor rrn6 (Protein from Saccharomyces cerevisiae)
- Non-template dna strand (DNA from synthetic construct)
- Rpab1_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc1 (Protein from Saccharomyces cerevisiae)
- Rpac1_yeast dna-directed rna polymerases i and iii subunit rpac1 (Protein from Saccharomyces cerevisiae)
- Rpab2_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc2 (Protein from Saccharomyces cerevisiae)
- Rpa49_yeast dna-directed rna polymerase i subunit (Protein from Saccharomyces cerevisiae)
- Rpab4_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc4 (Protein from Saccharomyces cerevisiae)
- Rpa34_yeast dna-directed rna polymerase i subunit rpa34 (Protein from Saccharomyces cerevisiae)
- Rpac2_yeast dna-directed rna polymerases i and iii subunit rpac2 (Protein from Saccharomyces cerevisiae)
- Rpa14_yeast dna-directed rna polymerase i subunit rpa14 (Protein from Saccharomyces cerevisiae)
- Rrn7_yeast rna polymerase i-specific transcription initiation factor rrn7 (Protein from Saccharomyces cerevisiae)
- Rna polymerase i pre-initiation complex with core factor, rrn3 and transcription scaffold (Complex)
- Rpab3_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc3 (Protein from Saccharomyces cerevisiae)
- Rpa43_yeast dna-directed rna polymerase i subunit (Protein from Saccharomyces cerevisiae)
- Rpab5_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc5 (Protein from Saccharomyces cerevisiae)
- Rpa1_yeast dna-directed rna polymerase i subunit rpa190 (Protein from Saccharomyces cerevisiae)
- Rrn11_yeast rna polymerase i-specific transcription initiation factor rrn11 (Protein from Saccharomyces cerevisiae)
- Template dna strand (DNA from synthetic construct)
- Rna polymerase i pre-initiation complex with core factor, rrn3 and transcription scaffold (875 MDa, Complex)
- Rpa12_yeast dna-directed rna polymerase i subunit rpa12 (Protein from Saccharomyces cerevisiae)
- Rpa2_yeast dna-directed rna polymerase i subunit rpa135 (Protein from Saccharomyces cerevisiae)
RNA polymerase I pre-initiation complex (CF focused refinement)
Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Muller CW
EMBO J (2017) 36 pp. 2698-2709 [ Pubmed: 28739580 DOI: doi:10.15252/embj.201796958 ]
- Rrn11_yeast rna polymerase i-specific transcription initiation factor rrn11 (Protein)
- Rrn6_yeast rna polymerase i-specific transcription initiation factor rrn6 (Protein)
- Rna polymerase i pre-initiation complex with core factor, rrn3 and transcription scaffold (Complex from Saccharomyces cerevisiae)
- Template strand dna (DNA)
- Non-template strand dna (DNA)
- Rrn7_yeast rna polymerase i-specific transcription initiation factor rrn7 (Protein)
RNA polymerase I pre-initiation complex (Pol-Rrn3 focused refinement)
Sadian Y, Tafur L, Kosinski J, Jakobi AJ, Wetzel R, Buczak K, Hagen WJ, Beck M, Sachse C, Muller CW
EMBO J (2017) 36 pp. 2698-2709 [ Pubmed: 28739580 DOI: doi:10.15252/embj.201796958 ]
- Rpa1_yeast dna-directed rna polymerase i subunit rpa190 (Protein)
- Rpa34_yeast dna-directed rna polymerase i subunit rpa34 (Protein)
- Rpab4_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc4 (Protein)
- Rrn3_yeast rna polymerase i-specific transcription initiation factor rrn3 (Protein)
- Rpab3_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc3 (Protein)
- Rpa43_yeast dna-directed rna polymerase i subunit rpa43 (Protein)
- Rpa49_yeast dna-directed rna polymerase i subunit rpa49 (Protein)
- Template dna strand (DNA)
- Rpac2_yeast dna-directed rna polymerases i and iii subunit rpac2 (Protein)
- Non-template dna strand (DNA)
- Rna polymerase i pre-initiation complex with core factor, rrn3 and transcription scaffold (Complex from Saccharomyces cerevisiae)
- Rpab1_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc1 (Protein)
- Rpab5_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc5 (Protein)
- Rpa12_yeast dna-directed rna polymerase i subunit rpa12 (Protein)
- Rpa2_yeast dna-directed rna polymerase i subunit rpa135 (Protein)
- Rpa14_yeast dna-directed rna polymerase i subunit rpa14 (Protein)
- Rpac1_yeast dna-directed rna polymerases i and iii subunit rpac1 (Protein)
- Rpab2_yeast dna-directed rna polymerases i, ii, and iii subunit rpabc2 (Protein)
RNA Polymerase I elongation complex 1
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5m5x
Q-score: 0.302
Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Muller CW
Mol Cell (2016) 64 pp. 1135-1143 [ DOI: doi:10.1016/j.molcel.2016.11.013 Pubmed: 27867008 ]
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa49 (46 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (16 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa34 (26 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (25 kDa, Protein from Saccharomyces cerevisiae)
- Rna polymerase i elongation complex 1 (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac1 (37 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (17 kDa, Protein from Saccharomyces cerevisiae)
- Rna (6 kDa, RNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa135 (135 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa43 (36 kDa, Protein from Saccharomyces cerevisiae)
- Template dna (11 kDa, DNA from Saccharomyces cerevisiae)
- Transcription scaffold (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac2 (16 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa14 (14 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa190 (186 kDa, Protein from Saccharomyces cerevisiae)
- Non-template dna (11 kDa, DNA from Saccharomyces cerevisiae)
RNA Polymerase I elongation complex 2
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5m5y
Q-score: 0.308
Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Muller CW
Mol Cell (2016) 64 pp. 1135-1143 [ DOI: doi:10.1016/j.molcel.2016.11.013 Pubmed: 27867008 ]
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Saccharomyces cerevisiae)
- Transcription scaffold (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Saccharomyces cerevisiae)
- Rna (3 kDa, RNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa49 (46 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (16 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa34 (26 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (25 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac1 (37 kDa, Protein from Saccharomyces cerevisiae)
- Rna polymerase i elongation complex 2 (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (17 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa135 (135 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa43 (36 kDa, Protein from Saccharomyces cerevisiae)
- Template dna (21 kDa, DNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac2 (16 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa14 (14 kDa, Protein from Saccharomyces cerevisiae)
- Non-template dna (22 kDa, DNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa190 (186 kDa, Protein from Saccharomyces cerevisiae)
RNA Polymerase I elongation complex with A49 tandem winged helix domain
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 5m64
Q-score: 0.266
Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Muller CW
Mol Cell (2016) 64 pp. 1135-1143 [ DOI: doi:10.1016/j.molcel.2016.11.013 Pubmed: 27867008 ]
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Saccharomyces cerevisiae)
- Rna (3 kDa, RNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa49 (46 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (16 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa34 (26 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (25 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac1 (37 kDa, Protein from Saccharomyces cerevisiae)
- Transcription scaffold (10 kDa, Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (17 kDa, Protein from Saccharomyces cerevisiae)
- Rna polymerase i elongation complex with a49 tandem winged helix domain (600 kDa, Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa135 (135 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa43 (36 kDa, Protein from Saccharomyces cerevisiae)
- Template dna (21 kDa, DNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac2 (16 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa14 (14 kDa, Protein from Saccharomyces cerevisiae)
- Non-template dna (22 kDa, DNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa190 (186 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5m5w
Q-score: 0.362
Tafur L, Sadian Y, Hoffmann NA, Jakobi AJ, Wetzel R, Hagen WJ, Sachse C, Muller CW
Mol Cell (2016) 64 pp. 1135-1143 [ DOI: doi:10.1016/j.molcel.2016.11.013 Pubmed: 27867008 ]
- Dna-directed rna polymerase i subunit rpa190 (186 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerase i subunit rpa43 (36 kDa, Protein from Saccharomyces cerevisiae S288c)
- Transcription scaffold (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerase i subunit rpa14 (14 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (17 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerases i and iii subunit rpac2 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerase i subunit rpa34 (26 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Saccharomyces cerevisiae S288c)
- Non-template strand (22 kDa, DNA from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i and iii subunit rpac1 (37 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (25 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerase i subunit rpa135 (135 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Saccharomyces cerevisiae S288c)
- Dna-directed rna polymerase i subunit rpa49 (46 kDa, Protein from Saccharomyces cerevisiae S288c)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (16 kDa, Protein from Saccharomyces cerevisiae S288c)
- Template strand (21 kDa, DNA from Saccharomyces cerevisiae)
- Rna polymerase i open complex (Complex from Saccharomyces cerevisiae)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (8 kDa, Protein from Saccharomyces cerevisiae S288c)