Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with Gi1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xbw
Q-score: 0.468
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Chemokine receptor cx3cr1 in complex with gi1 (Complex from Homo sapiens)
- Cx3c chemokine receptor 1 (41 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xbx
Q-score: 0.361
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q
Sci Adv (2022) 8 pp. eabn8048-eabn8048 [ DOI: doi:10.1126/sciadv.abn8048 Pubmed: 35767622 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Chemokine receptor cx3cr1 in complex with cx3cl1 gi1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Processed fractalkine,cx3c chemokine receptor 1 (51 kDa, Protein from Homo sapiens)
Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7x9a
Q-score: 0.411
Tang T, Tan Q, Han S, Diemar A, Lobner K, Wang H, Schuss C, Behr V, Morl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B
Sci Adv (2022) 8 pp. eabm1232-eabm1232 [ DOI: doi:10.1126/sciadv.abm1232 Pubmed: 35507650 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 1 (43 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor and gi (Complex)
- Neuropeptide y (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor in complex with npy and gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7x9b
Q-score: 0.394
Tang T, Tan Q, Han S, Diemar A, Lobner K, Wang H, Schuss C, Behr V, Morl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B
Sci Adv (2022) 8 pp. eabm1232-eabm1232 [ DOI: doi:10.1126/sciadv.abm1232 Pubmed: 35507650 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y y2 receptor and gi (Complex)
- Neuropeptide y (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Neuropeptide y y2 receptor in complex with npy and gi (Complex from Homo sapiens)
Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7x9c
Q-score: 0.443
Tang T, Tan Q, Han S, Diemar A, Lobner K, Wang H, Schuss C, Behr V, Morl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, Kaiser A, Beck-Sickinger AG, Zhao Q, Wu B
Sci Adv (2022) 8 pp. eabm1232-eabm1232 [ DOI: doi:10.1126/sciadv.abm1232 Pubmed: 35507650 ]
- Neuropeptide y y4 receptor and gi (Complex)
- Neuropeptide y receptor type 4 (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Pancreatic polypeptide (Complex)
- Neuropeptide y y4 receptor in complex with pp and gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Pancreatic hormone (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7f8v
Q-score: 0.436
Zhang X, He C, Wang M, Zhou Q, Yang D, Zhu Y, Feng W, Zhang H, Dai A, Chu X, Wang J, Yang Z, Jiang Y, Sensfuss U, Tan Q, Han S, Reedtz-Runge S, Xu HE, Zhao S, Wang MW, Wu B, Zhao Q
Nat Chem Biol (2021) 17 pp. 1230-1237 [ DOI: doi:10.1038/s41589-021-00866-8 Pubmed: 34556863 ]
- Cholecystokinin recetor cckbr in complex with gastrin-17 and gi (Complex from Homo sapiens)
- Cholecystokinin type b receptor (Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-2 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Gastrin-17 (2 kDa, Protein from Homo sapiens)
- Gastrin/cholecystokinin type b receptor (50 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit (Complex)
- Gastrin-17 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7f8w
Q-score: 0.335
Zhang X, He C, Wang M, Zhou Q, Yang D, Zhu Y, Feng W, Zhang H, Dai A, Chu X, Wang J, Yang Z, Jiang Y, Sensfuss U, Tan Q, Han S, Reedtz-Runge S, Xu HE, Zhao S, Wang MW, Wu B, Zhao Q
Nat Chem Biol (2021) 17 pp. 1230-1237 [ DOI: doi:10.1038/s41589-021-00866-8 Pubmed: 34556863 ]
- Cholecystokinin type b receptor (Complex)
- Gastrin-17 (2 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g subunits (Complex from Homo sapiens)
- Cholecystokinin recetor cckbr in complex with gastrin-17 and gq (Complex from Homo sapiens)
- Gastrin/cholecystokinin type b receptor (50 kDa, Protein from Homo sapiens)
- Gastrin-17 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Scfv16 (28 kDa, Protein from Homo sapiens)
Cryo-EM structure of the chemokine receptor CCR5 in complex with MIP-1a and Gi
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7f1q
Q-score: 0.48
Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B
Nat Commun (2021) 12 pp. 4151-4151 [ DOI: doi:10.1038/s41467-021-24438-5 Pubmed: 34230484 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemokine receptor ccr5 in complex with mip-1a and gi (Complex from Homo sapiens)
- C-c motif chemokine 3,c-c chemokine receptor type 5 (51 kDa, Protein from Homo sapiens)
Cryo-EM structure of the chemokine receptor CCR5 in complex with RANTES and Gi
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7f1r
Q-score: 0.439
Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B
Nat Commun (2021) 12 pp. 4151-4151 [ DOI: doi:10.1038/s41467-021-24438-5 Pubmed: 34230484 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Chemokine receptor ccr5 in complex with rantes and gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- C-c motif chemokine 5,c-c chemokine receptor type 5 (52 kDa, Protein from Homo sapiens)
Cryo-EM structure of the apo chemokine receptor CCR5 in complex with Gi
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7f1s
Q-score: 0.447
Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B
Nat Commun (2021) 12 pp. 4151-4151 [ DOI: doi:10.1038/s41467-021-24438-5 Pubmed: 34230484 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- C-c chemokine receptor type 5 (42 kDa, Protein from Homo sapiens)
- Chemokine receptor ccr5 in complex with gi (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)