Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bu8
Q-score: 0.397
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7bua
Q-score: 0.249
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 6.5
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7bub
Q-score: 0.376
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Dengue virus serotype2 e protein (54 kDa, Protein from Dengue virus 2)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue virus serotype 2 m protein (8 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7bud
Q-score: 0.334
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue virus serotype 2 m protein (8 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 e protein (54 kDa, Protein from Dengue virus 2)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)
Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 5.0
Resolution: 7.8 Å
EM Method: Single-particle
Fitted PDBs: 7bue
Q-score: 0.129
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c fab (Complex from Homo sapiens)
- Dengue serotype 2 e protein ectodomain (43 kDa, Protein from Dengue virus 2)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 (Complex)
- Sign-3c fab (Complex from Dengue virus 2)
Cryo-EM structure of Dengue virus serotype 2 complexed with SIgN-3C IgG
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 7buf
Q-score: 0.157
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Sign-3c igg light chain (11 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 m protein (8 kDa, Protein from Dengue virus 2)
- Sign-3c igg heavy chain (14 kDa, Protein from Homo sapiens)
- Complex of dengue virus serotype 2 with sign-3c igg (Complex from Homo sapiens)
- Dengue virus serotype 2 e protein (54 kDa, Protein from Dengue virus 2)
- Dengue virus serotype 2 (Complex)
- Sign-3c igg (Complex from Dengue virus 2)