Resolution: 4.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8s5m
Q-score: 0.222
McCorvie TJ, Adamoski D, Machado RAC, Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C, Basle A, Ambrosio ALB, Dias SMG, Yue WW
Nat Commun (2024) 15 pp. 2931-2931 [ DOI: doi:10.1038/s41467-024-46864-x Pubmed: 38575566 ]
McCorvie TJ, Adamoski D, Machado RAC, Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C, Basle A, Ambrosio ALB, Dias SMG, Yue WW
Nat Commun (2024) 15 pp. 2931-2931 [ DOI: doi:10.1038/s41467-024-46864-x Pubmed: 38575566 ]
McCorvie TJ, Adamoski D, Machado RAC, Tang J, Bailey HJ, Ferreira DSM, Strain-Damerell C, Basle A, Ambrosio ALB, Dias SMG, Yue WW
Nat Commun (2024) 15 pp. 2931-2931 [ DOI: doi:10.1038/s41467-024-46864-x Pubmed: 38575566 ]
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7tj8
Q-score: 0.512
Noland CL, Chua HC, Kschonsak M, Heusser SA, Braun N, Chang T, Tam C, Tang J, Arthur CP, Ciferri C, Pless SA, Payandeh J
Nat Commun (2022) 13 pp. 1416-1416 [ DOI: doi:10.1038/s41467-022-28984-4 Pubmed: 35301303 ]
- Sodium channel subunit beta-3 (24 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Complex of human nax with the beta3 auxiliary subunit (Complex from Homo sapiens)
- Sodium channel protein type 7 subunit alpha (199 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7tj9
Q-score: 0.565
Noland CL, Chua HC, Kschonsak M, Heusser SA, Braun N, Chang T, Tam C, Tang J, Arthur CP, Ciferri C, Pless SA, Payandeh J
Nat Commun (2022) 13 pp. 1416-1416 [ Pubmed: 35301303 DOI: doi:10.1038/s41467-022-28984-4 ]
- 2-{[(4-o-alpha-d-glucopyranosyl-alpha-d-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25r)-spirost-5-en-3-yl]oxy}butyl 4-o-alpha-d-glucopyranosyl-alpha-d-glucopyranoside (1 kDa, Ligand)
- Sodium channel subunit beta-3 (24 kDa, Protein from Homo sapiens)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex between human nax and the beta3 auxiliary subunit (Complex from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Sodium channel protein type 7 subunit alpha (199 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)