Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
Resolution: 4.24 Å
EM Method: Single-particle
Fitted PDBs: 8pjj
Q-score: 0.218
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Sl7uuc rna (19 kDa, RNA from Drosophila melanogaster)
- Sl7uuc rna (Complex from Drosophila melanogaster)
- Complex of mle, sl7uuc and adp (150 kDa, Complex)
- Dosage compensation regulator (Complex from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8pjb
Q-score: 0.415
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (Complex from Drosophila melanogaster)
- Complex of mle, uuc and adp (134 kDa, Complex)
- Rna (5'-r(p*cp*up*cp*up*up*up*cp*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Dosage compensation regulator (Complex from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8b9g
Q-score: 0.513
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Rna (5'-r(p*up*up*up*up*up*up*up*up*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Mle in complex with adp:alf4 and u10 rna (133 kDa, Complex from Drosophila melanogaster)
- Water (18 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8b9i
Q-score: 0.469
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Mle in complex with adp:alf4 and uuc rna (133 kDa, Complex from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Rna (5'-r(p*cp*cp*up*cp*up*up*up*cp*up*up*u)-3') (3 kDa, RNA from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9j
Q-score: 0.416
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Mle in complex with adp:alf4 (130 kDa, Cellular component from Drosophila melanogaster)
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 8b9k
Q-score: 0.239
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Sl7moduuc (19 kDa, RNA from Drosophila melanogaster)
- Mle in complex with adp:alf4 and sl7moduuc rna (149 kDa, Complex from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)
- Tetrafluoroaluminate ion (102 Da, Ligand)
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8b9l
Q-score: 0.345
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K, Beck M, Becker PB, Hennig J
Mol Cell (2023) 83 pp. 4318-4333.e10 [ DOI: doi:10.1016/j.molcel.2023.10.026 Pubmed: 37989319 ]
- Mle (130 kDa, Cellular component from Drosophila melanogaster)
- Dosage compensation regulator (130 kDa, Protein from Drosophila melanogaster)