Structure of the plasma coagulation Factor XIII A2B2 heterotetrameric complex.
Singh S, Hagelueken G, Ugurlar D, Ramaraje Urs SU, Sharma A, Mahapatra M, Drepper F, Imhof D, Huesgen PF, Oldenburg J, Geyer M, Biswas A
Blood (2025) 145 pp. 438-449 [ DOI: doi:10.1182/blood.2024025369 Pubmed: 39447073 ]
- Coagulation factor xiii b chain (75 kDa, Protein from Homo sapiens)
- Coagulation factor xiii a chain (83 kDa, Protein from Homo sapiens)
- Factor xiii a2b2 heterotetramer (Complex from Homo sapiens)
High resolution structure of the coagulation Factor XIII A2B2 heterotetramer complex.
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 8cmu
Q-score: 0.601
Singh S, Hagelueken G, Ugurlar D, Ramaraje Urs SU, Sharma A, Mahapatra M, Drepper F, Imhof D, Huesgen PF, Oldenburg J, Geyer M, Biswas A
Blood (2025) 145 pp. 438-449 [ DOI: doi:10.1182/blood.2024025369 Pubmed: 39447073 ]
- Water (18 Da, Ligand)
- Coagulation factor xiii b chain (75 kDa, Protein from Homo sapiens)
- Coagulation factor xiii a chain (83 kDa, Protein from Homo sapiens)
- Factor xiii a2b2 heterotetramer (Complex from Homo sapiens)
Cryo-electron tomography average of an C1-IgG complex
Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJR, van de Winkel JGJ, Wilson IA, Koster AJ, Taylor RP, Ollmann Saphire E, Burton DR, Schuurman J, Gros P, Parren PWHI
Science (2014) 343 pp. 1260-1263 [ Pubmed: 24626930 DOI: doi:10.1126/science.1248943 ]
- Polyclonal igg (150 kDa, Protein from Capra hircus)
- C1 (766 kDa, Protein from Homo sapiens)
- Dnp-haptenated liposomes, polyclonal goat anti-dnp antibody, human c1 (originating from c4 depleted serum) (1 MDa, Sample)
Cryo-electron tomography average of an C1-IgG complex
Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJR, van de Winkel JGJ, Wilson IA, Koster AJ, Taylor RP, Ollmann-Saphire E, Burton DR, Schuurman J, Gros P, Parren PWHI
Science (2014) 343 pp. 1260-1263 [ Pubmed: 24626930 DOI: doi:10.1126/science.1248943 ]
- Dnp-haptenated liposomes, polyconal goat anti-dnp antibody, human c1 (originating from c4 depleted serum) (1 MDa, Sample)
- Polyclonal igg (150 kDa, Protein from Capra hircus)
- C1 (766 kDa, Protein from Homo sapiens)
electron tomography average of an IgG hexamer
Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJR, van de Winkel JGJ, Wilson IA, Koster AJ, Taylor RP, Ollmann-Saphire E, Burton DR, Schuurman J, Gros P, Parren PWHI
Science (2014) 343 pp. 1260-1263 [ Pubmed: 24626930 DOI: doi:10.1126/science.1248943 ]
- Igg1-005-e345r-e430g-s440y (148 kDa, Protein from Homo sapiens)
- Igg1-005-rgy monoclonal antibody (890 kDa, Sample)