Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8tb7
Q-score: 0.517
Lees JA, Dias JM, Rajamohan F, Fortin JP, O'Connor R, Kong JX, Hughes EAG, Fisher EL, Tuttle JB, Lovett G, Kormos BL, Unwalla RJ, Zhang L, Dechert Schmitt AM, Zhou D, Moran M, Stevens KA, Fennell KF, Varghese AE, Maxwell A, Cote EE, Zhang Y, Han S
Nat Commun (2023) 14 pp. 5938-5938 [ DOI: doi:10.1038/s41467-023-41646-3 Pubmed: 37741852 ]
- Water (18 Da, Ligand)
- Fab hinge-binding nanobody (13 kDa, Protein from Lama glama)
- G-protein coupled receptor 61,soluble cytochrome b562 (59 kDa, Protein from Homo sapiens)
- Gpr61-icl3-bril chimera in complex with anti-bril fab24 bak5 and hinge-binding nanobody bound to inverse agonist compound 1 (Complex from Homo sapiens)
- Fab24 bak5 heavy chain (52 kDa, Protein from Homo sapiens)
- 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-n-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-n-(2-methoxyethyl)pyridine-3-sulfonamide (524 Da, Ligand)
- Fab24 bak5 light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8e4y
Q-score: 0.502
Johnson ZL, Ammirati M, Wasilko DJ, Chang JS, Noell S, Foley TL, Yoon H, Smith K, Asano S, Hales K, Wan M, Yang Q, Piotrowski MA, Farley KA, Gilbert T, Aschenbrenner LM, Fennell KF, Dutra JK, Xu M, Guo C, Varghese AE, Bellenger J, Quinn A, Am Ende CW, West GM, Griffor MC, Bennett D, Calabrese M, Steppan CM, Han S, Wu H
Nat Struct Mol Biol (2023) 30 pp. 22-30 [ Pubmed: 36522428 DOI: doi:10.1038/s41594-022-00884-7 ]
- [(2r,3s,4r,5r)-5-(6-amino-9h-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methyl (3r)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(2-oxohexadecyl)sulfanyl]ethyl}amino)propyl]amino}butyl dihydrogen diphosphate (non-preferred name) (1 kDa, Ligand)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate (410 Da, Ligand)
- Glycerol-3-phosphate acyltransferase 1, mitochondrial (86 kDa, Protein from Homo sapiens)
- Glycerol-3-phosphate acyltransferase 1 (86 kDa, Complex from Homo sapiens)
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8e50
Q-score: 0.444
Johnson ZL, Ammirati M, Wasilko DJ, Chang JS, Noell S, Foley TL, Yoon H, Smith K, Asano S, Hales K, Wan M, Yang Q, Piotrowski MA, Farley KA, Gilbert T, Aschenbrenner LM, Fennell KF, Dutra JK, Xu M, Guo C, Varghese AE, Bellenger J, Quinn A, Am Ende CW, West GM, Griffor MC, Bennett D, Calabrese M, Steppan CM, Han S, Wu H
Nat Struct Mol Biol (2023) 30 pp. 22-30 [ Pubmed: 36522428 DOI: doi:10.1038/s41594-022-00884-7 ]
- Coenzyme a (767 Da, Ligand)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate (410 Da, Ligand)
- Glycerol-3-phosphate acyltransferase 1, mitochondrial (86 kDa, Protein from Homo sapiens)
- Glycerol-3-phosphate acyltransferase 1 (86 kDa, Complex from Homo sapiens)