SARS-CoV-2 S B.1.529 Omicron variant (RBD + S309 Local Refinement)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7tly
Q-score: 0.528
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- Sars-cov-2 s rbd b.1.1.529 omicron variant + s309 (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 S NTD B.1.1.529 Omicron variant + S309 Local Refinement
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7tlz
Q-score: 0.52
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain (11 kDa, Protein from Homo sapiens)
- S2l20 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 s ntd b.1.1.529 omicron variant + s2l20 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Homo sapiens)
SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7tm0
Q-score: 0.401
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2l20 fab heavy chain (13 kDa, Protein from Homo sapiens)
- S309 fab light chain (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 s rbd b.1.1.529 omicron variant + s309 (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 fab heavy chain (14 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike protein bound to the S2P6 and S2M11 Fab fragments
Pinto D, Sauer MM, Czudnochowski N, Low JS, Tortorici MA, Housley MP, Noack J, Walls AC, Bowen JE, Guarino B, Rosen LE, di Iulio J, Jerak J, Kaiser H, Islam S, Jaconi S, Sprugasci N, Culap K, Abdelnabi R, Foo C, Coelmont L, Bartha I, Bianchi S, Silacci-Fregni C, Bassi J, Marzi R, Vetti E, Cassotta A, Ceschi A, Ferrari P, Cippa PE, Giannini O, Ceruti S, Garzoni C, Riva A, Benigni F, Cameroni E, Piccoli L, Pizzuto MS, Smithey M, Hong D, Telenti A, Lempp FA, Neyts J, Havenar-Daughton C, Lanzavecchia A, Sallusto F, Snell G, Virgin HW, Beltramello M, Corti D, Veesler D
Science (2021) 373 pp. 1109-1116 [ Pubmed: 34344823 DOI: doi:10.1126/science.abj3321 ]
- S2m11 fab fragment (Complex from Homo sapiens)
- S2p6 and s2m11 fab fragments bound to the sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2p6 fab fragment (Complex from Homo sapiens)
SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7k43
Q-score: 0.573
Tortorici MA, Beltramello M, Lempp FA, Pinto D, Dang HV, Rosen LE, McCallum M, Bowen J, Minola A, Jaconi S, Zatta F, De Marco A, Guarino B, Bianchi S, Lauron EJ, Tucker H, Zhou J, Peter A, Havenar-Daughton C, Wojcechowskyj JA, Case JB, Chen RE, Kaiser H, Montiel-Ruiz M, Meury M, Czudnochowski N, Spreafico R, Dillen J, Ng C, Sprugasci N, Culap K, Benigni F, Abdelnabi R, Foo SC, Schmid MA, Cameroni E, Riva A, Gabrieli A, Galli M, Pizzuto MS, Neyts J, Diamond MS, Virgin HW, Snell G, Corti D, Fink K, Veesler D
Science (2020) 370 pp. 950-957 [ Pubmed: 32972994 DOI: doi:10.1126/science.abe3354 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2m11 fab fragment (light chain) (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with the s2m11 neutralizing antibody fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2m11 fab fragment (heavy chain) (13 kDa, Protein from Homo sapiens)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7k45
Q-score: 0.432
Tortorici MA, Beltramello M, Lempp FA, Pinto D, Dang HV, Rosen LE, McCallum M, Bowen J, Minola A, Jaconi S, Zatta F, De Marco A, Guarino B, Bianchi S, Lauron EJ, Tucker H, Zhou J, Peter A, Havenar-Daughton C, Wojcechowskyj JA, Case JB, Chen RE, Kaiser H, Montiel-Ruiz M, Meury M, Czudnochowski N, Spreafico R, Dillen J, Ng C, Sprugasci N, Culap K, Benigni F, Abdelnabi R, Foo SC, Schmid MA, Cameroni E, Riva A, Gabrieli A, Galli M, Pizzuto MS, Neyts J, Diamond MS, Virgin HW, Snell G, Corti D, Fink K, Veesler D
Science (2020) 370 pp. 950-957 [ Pubmed: 32972994 DOI: doi:10.1126/science.abe3354 ]
- S2e12 neutralizing antibody fab fragment (light chain) (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with the s2e12 neutralizing antibody fab fragment (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2e12 neutralizing antibody fab fragment (heavy chain) (13 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7k4n
Q-score: 0.422
Tortorici MA, Beltramello M, Lempp FA, Pinto D, Dang HV, Rosen LE, McCallum M, Bowen J, Minola A, Jaconi S, Zatta F, De Marco A, Guarino B, Bianchi S, Lauron EJ, Tucker H, Zhou J, Peter A, Havenar-Daughton C, Wojcechowskyj JA, Case JB, Chen RE, Kaiser H, Montiel-Ruiz M, Meury M, Czudnochowski N, Spreafico R, Dillen J, Ng C, Sprugasci N, Culap K, Benigni F, Abdelnabi R, Foo SC, Schmid MA, Cameroni E, Riva A, Gabrieli A, Galli M, Pizzuto MS, Neyts J, Diamond MS, Virgin HW, Snell G, Corti D, Fink K, Veesler D
Science (2020) 370 pp. 950-957 [ Pubmed: 32972994 DOI: doi:10.1126/science.abe3354 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2e12 neutralizing antibody fab fragment (light chain) (11 kDa, Protein from Homo sapiens)
- S2e12 neutralizing antibody fab fragment (heavy chain) (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with the s2e12 neutralizing antibody fab fragment (Complex from Severe acute respiratory syndrome coronavirus 2)