N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8g30
Q-score: 0.487
Momont C, Dang HV, Zatta F, Hauser K, Wang C, di Iulio J, Minola A, Czudnochowski N, De Marco A, Branch K, Donermeyer D, Vyas S, Chen A, Ferri E, Guarino B, Powell AE, Spreafico R, Yim SS, Balce DR, Bartha I, Meury M, Croll TI, Belnap DM, Schmid MA, Schaiff WT, Miller JL, Cameroni E, Telenti A, Virgin HW, Rosen LE, Purcell LA, Lanzavecchia A, Snell G, Corti D, Pizzuto MS
Nature (2023) 618 pp. 590-597 [ Pubmed: 37258672 DOI: doi:10.1038/s41586-023-06136-y ]
- Calcium ion (40 Da, Ligand)
- N2 neuraminidase of a/tanzania/205/2010 h3n2 in complex with 4 fni19 fab molecules (420 kDa, Complex from Influenza A virus)
- Neuraminidase (54 kDa, Protein from Influenza A virus)
- Fni19 fab light chain (23 kDa, Protein from Homo sapiens)
- Fni19 fab heavy chain (24 kDa, Protein from Homo sapiens)
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 3 FNI9 Fab molecules
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8g3m
Q-score: 0.502
Momont C, Dang HV, Zatta F, Hauser K, Wang C, di Iulio J, Minola A, Czudnochowski N, De Marco A, Branch K, Donermeyer D, Vyas S, Chen A, Ferri E, Guarino B, Powell AE, Spreafico R, Yim SS, Balce DR, Bartha I, Meury M, Croll TI, Belnap DM, Schmid MA, Schaiff WT, Miller JL, Cameroni E, Telenti A, Virgin HW, Rosen LE, Purcell LA, Lanzavecchia A, Snell G, Corti D, Pizzuto MS
Nature (2023) 618 pp. 590-597 [ Pubmed: 37258672 DOI: doi:10.1038/s41586-023-06136-y ]
- Calcium ion (40 Da, Ligand)
- N2 neuraminidase of a/tanzania/205/2010 h3n2 in complex with 3 fni9 fab molecules (420 kDa, Complex from Influenza A virus)
- Fni9 fab light chain (23 kDa, Protein from Homo sapiens)
- Neuraminidase (54 kDa, Protein from Influenza A virus)
- Fni9 fab heavy chain (24 kDa, Protein from Homo sapiens)
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI9 Fab molecules
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8g3o
Q-score: 0.517
Momont C, Dang HV, Zatta F, Hauser K, Wang C, di Iulio J, Minola A, Czudnochowski N, De Marco A, Branch K, Donermeyer D, Vyas S, Chen A, Ferri E, Guarino B, Powell AE, Spreafico R, Yim SS, Balce DR, Bartha I, Meury M, Croll TI, Belnap DM, Schmid MA, Schaiff WT, Miller JL, Cameroni E, Telenti A, Virgin HW, Rosen LE, Purcell LA, Lanzavecchia A, Snell G, Corti D, Pizzuto MS
Nature (2023) 618 pp. 590-597 [ Pubmed: 37258672 DOI: doi:10.1038/s41586-023-06136-y ]
- Calcium ion (40 Da, Ligand)
- Neuraminidase (54 kDa, Protein from Influenza A virus)
- Fni9 fab light chain (23 kDa, Protein from Homo sapiens)
- 3 fni9 fabs in complex with tetrameric n2 na protein from a/hong_kong/2671/2019 strain (420 kDa, Complex from Influenza A virus)
- Fni9 fab heavy chain (24 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8erq
Q-score: 0.493
Park YJ, Pinto D, Walls AC, Liu Z, De Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko NM, Logue JK, Dang HV, Hauser K, di Iulio J, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu HY, Pizzuto MS, Corti D, Veesler D
Science (2022) 378 pp. 619-627 [ Pubmed: 36264829 DOI: doi:10.1126/science.adc9127 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 ba.1 spike ectodomain trimer in complex with the s2x324 neutralizing antibody fab fragment (local refinement of the rbd and s2x324) (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2x324 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2x324 fab (Complex from Homo sapiens)
- S2x324 fab light chain (11 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8err
Q-score: 0.449
Park YJ, Pinto D, Walls AC, Liu Z, De Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko NM, Logue JK, Dang HV, Hauser K, di Iulio J, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu HY, Pizzuto MS, Corti D, Veesler D
Science (2022) 378 pp. 619-627 [ Pubmed: 36264829 DOI: doi:10.1126/science.adc9127 ]
- S2x324 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2x324 light chain (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron ba.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron ba.1 spike ectodomain trimer in complex with the s2x324 neutralizing antibody fab fragment (Complex from Severe acute respiratory syndrome coronavirus 2)
- S2x324 fab (Complex from Homo sapiens)
SARS-CoV-2 S B.1.529 Omicron variant (RBD + S309 Local Refinement)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7tly
Q-score: 0.528
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- Sars-cov-2 s rbd b.1.1.529 omicron variant + s309 (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 S NTD B.1.1.529 Omicron variant + S309 Local Refinement
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7tlz
Q-score: 0.52
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain (11 kDa, Protein from Homo sapiens)
- S2l20 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Sars-cov-2 s ntd b.1.1.529 omicron variant + s2l20 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (141 kDa, Protein from Homo sapiens)
SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7tm0
Q-score: 0.401
McCallum M, Czudnochowski N, Rosen LE, Zepeda SK, Bowen JE, Walls AC, Hauser K, Joshi A, Stewart C, Dillen JR, Powell AE, Croll TI, Nix J, Virgin HW, Corti D, Snell G, Veesler D
Science (2022) 375 pp. 864-868 [ Pubmed: 35076256 DOI: doi:10.1126/science.abn8652 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S2l20 fab light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S2l20 fab heavy chain (13 kDa, Protein from Homo sapiens)
- S309 fab light chain (11 kDa, Protein from Homo sapiens)
- Sars-cov-2 s rbd b.1.1.529 omicron variant + s309 (Complex from Severe acute respiratory syndrome coronavirus 2)
- S309 fab heavy chain (14 kDa, Protein from Homo sapiens)
Park YJ, De Marco A, Starr TN, Liu Z, Pinto D, Walls AC, Zatta F, Zepeda SK, Bowen JE, Sprouse KR, Joshi A, Giurdanella M, Guarino B, Noack J, Abdelnabi R, Foo SC, Rosen LE, Lempp FA, Benigni F, Snell G, Neyts J, Whelan SPJ, Virgin HW, Bloom JD, Corti D, Pizzuto MS, Veesler D
Science (2022) 375 pp. 449-454 [ DOI: doi:10.1126/science.abm8143 Pubmed: 34990214 ]
- S2k146 fab heavy chain (Protein from Homo sapiens)
- Sars-cov-2 spike in complex with the s2k146 neutralizing antibody fab fragment (three receptor-binding domains open) (Complex from Homo sapiens)
- S2k146 (Complex from Homo sapiens)
- S2k146 fab light chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Protein from Severe acute respiratory syndrome coronavirus 2)