DH270.6 Fab bound to the HIV-1 CH848 DE3 SOSIP
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8vgv
Q-score: 0.453
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ Pubmed: 39489734 DOI: doi:10.1038/s41467-024-53120-9 ]
- Dh270.6 antibody fab heavy chain (14 kDa, Protein from Homo sapiens)
- Dh270.6 antibody fab light chain (11 kDa, Protein from Homo sapiens)
- Ch848 de3 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Ch848 de3 sosip gp120 (51 kDa, Protein from Human immunodeficiency virus 1)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
VRC01 Fab bound to the HIV-1 CH848 DE3 SOSIP
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8vgw
Q-score: 0.426
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ Pubmed: 39489734 DOI: doi:10.1038/s41467-024-53120-9 ]
- Ch848 de3 sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Vrc01 fab light chain (11 kDa, Protein from Homo sapiens)
- Ch848 de3 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc01 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
CH235.12 Fab bound to the HIV-1 CH505.M5 SOSIP
Resolution: 4.08 Å
EM Method: Single-particle
Fitted PDBs: 8vh1
Q-score: 0.404
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ Pubmed: 39489734 DOI: doi:10.1038/s41467-024-53120-9 ]
- Ch505.m5 sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Ch235.i60 fab light chain (23 kDa, Protein from Homo sapiens)
- Ch505.m5 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Ch235.i60 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
CH235.12 Fab bound to the HIV-1 CH505.M5 SOSIP
Resolution: 4.31 Å
EM Method: Single-particle
Fitted PDBs: 8vh2
Q-score: 0.32
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ DOI: doi:10.1038/s41467-024-53120-9 Pubmed: 39489734 ]
- Ch505.m5.g458y sosip gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (18 kDa, Protein from Human immunodeficiency virus 1)
- Ch235.12 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Ch235.12 fab light chain (23 kDa, Protein from Homo sapiens)
CryoEM structure of VRC01-CH848.0358.80
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 8sal
Q-score: 0.235
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Ch0848.3.d0358.80.06chim.ds.6r.sosip gp41 (17 kDa, Protein from HIV-1 06TG.HT008)
- Ch0848.3.d0358.80.06chim.ds.6r.sosip gp120 (53 kDa, Protein from HIV-1 06TG.HT008)
- Vcr01 variable heavy chain (13 kDa, Protein from Homo sapiens)
- Vcr01 variable light chain (11 kDa, Protein from Homo sapiens)
- Vrc01-ch848.0358.80 (Complex from Homo sapiens)
CryoEM structure of VRC01-CH848.0836.10
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8san
Q-score: 0.349
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Ch848.0836.10 gp120 (51 kDa, Protein from HIV-1 06TG.HT008)
- Ch848.0836.10 gp41 (17 kDa, Protein from HIV-1 06TG.HT008)
- Vcr01 variable heavy chain (24 kDa, Protein from Homo sapiens)
- Vrc01-ch848.0836.10 (Complex from Homo sapiens)
- Vcr01 variable light chain (23 kDa, Protein from Homo sapiens)
CryoEM structure of DH270.6-CH848.0526.25
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8saq
Q-score: 0.433
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Ch848.0526.25 gp120 (54 kDa, Protein from HIV-1 06TG.HT008)
- Dh270.6-ch848.0526.25 (Complex from Homo sapiens)
- Ch848.0526.25 gp41 (17 kDa, Protein from HIV-1 06TG.HT008)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dh270.6 variable light chain (11 kDa, Protein from Homo sapiens)
- Dh270.6 variable heavy chain (14 kDa, Protein from Homo sapiens)
CryoEM structure of DH270.6-CH848.10.17
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 8sar
Q-score: 0.402
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Dh270.6 variable heavy chain (14 kDa, Protein from Homo sapiens)
- Dh270.6 variable light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ch848.10.17 gp41 (14 kDa, Protein from HIV-1 06TG.HT008)
- Dh270.6-ch848.10.17 (Complex from Homo sapiens)
- Ch848.10.17 gp120 (51 kDa, Protein from HIV-1 06TG.HT008)
CryoEM structure of DH270.5-CH848.10.17
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8sas
Q-score: 0.333
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Dh270.5 variable light chain (11 kDa, Protein from Homo sapiens)
- Dh270.5-ch848.10.17 (Complex from Homo sapiens)
- Dh270.5 variable heavy chian (14 kDa, Protein from Homo sapiens)
- Ch848.10.17 gp41 (14 kDa, Protein from HIV-1 06TG.HT008)
- Ch848.10.17 gp120 (51 kDa, Protein from HIV-1 06TG.HT008)
CryoEM structure of VRC01-CH848.10.17
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 8sat
Q-score: 0.411
Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P
Nat Commun (2023) 14 pp. 2782-2782 [ DOI: doi:10.1038/s41467-023-38108-1 Pubmed: 37188681 ]
- Vrc01-ch848.10.17 (Complex from Homo sapiens)
- Ch848.10.17 gp41 (17 kDa, Protein from HIV-1 06TG.HT008)
- Ch848.10.17 gp120 (52 kDa, Protein from HIV-1 06TG.HT008)
- Vrc01-variable heavy chain (13 kDa, Protein from Homo sapiens)
- Vrc01-variable light chain (11 kDa, Protein from Homo sapiens)