Structure of NaCT-PF4a complex
Resolution: 2.13 Å
EM Method: Single-particle
Fitted PDBs: 8uvb
Q-score: 0.618
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- (2r)-2-hydroxy-2-[2-(2-methoxy-5-methylpyridin-3-yl)ethyl]butanedioic acid (283 Da, Ligand)
- Dimer of nact in complex with pf4a (63 kDa, Complex from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Solute carrier family 13 member 5 (63 kDa, Protein from Homo sapiens)
Structure of NaDC3-aKG complex
Resolution: 2.09 Å
EM Method: Single-particle
Fitted PDBs: 8uvc
Q-score: 0.638
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- 2-oxoglutaric acid (146 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Dimer of nadc3 in complex with alpha-ketoglutarate (63 kDa, Complex from Homo sapiens)
Structure of NaDC3-PF4a complex
Resolution: 2.16 Å
EM Method: Single-particle
Fitted PDBs: 8uvd
Q-score: 0.625
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Dimer of nadc3 in complex with pf4a (63 kDa, Complex from Homo sapiens)
- (2r)-2-hydroxy-2-[2-(2-methoxy-5-methylpyridin-3-yl)ethyl]butanedioic acid (283 Da, Ligand)
Structure of NaDC3-Succinate complex in Coo-Ci conformation
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8uve
Q-score: 0.551
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Succinic acid (118 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Dimer of nadc3 in complex with succinate (63 kDa, Complex from Homo sapiens)
Structure of NaDC3-DMS complex in Ci-Ci conformation
Resolution: 2.17 Å
EM Method: Single-particle
Fitted PDBs: 8uvf
Q-score: 0.635
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Dimer of nadc3 in complex with 2,3-dms (63 kDa, Complex from Homo sapiens)
Structure of NaDC3-DMS complex in Co-Ci conformation
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8uvg
Q-score: 0.517
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- (2r,3s)-2,3-dimethylbutanedioic acid (146 Da, Ligand)
- Dimer of nadc3 in complex with 2,3-dms (63 kDa, Complex from Homo sapiens)
Structure of NaCT-succ complex
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8uvh
Q-score: 0.57
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Solute carrier family 13 member 5 (63 kDa, Protein from Homo sapiens)
- Dimer of nact complex in succinate (63 kDa, Complex from Homo sapiens)
Structure of NaDC3-Succinate complex in Coo-Coo conformation
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8uvi
Q-score: 0.548
Li Y, Song J, Mikusevic V, Marden JJ, Becerril A, Kuang H, Wang B, Rice WJ, Mindell JA, Wang DN
Nat Struct Mol Biol (2024) [ Pubmed: 39622972 DOI: doi:10.1038/s41594-024-01433-0 ]
- Tetradecane (198 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Succinic acid (118 Da, Ligand)
- Na(+)/dicarboxylate cotransporter 3 (67 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Dimer of nadc3 in complex with succinate (63 kDa, Complex from Homo sapiens)
Structure of enterovirus protease in complex host factor
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8x8q
Q-score: 0.544
Gao X, Wang B, Zhu K, Wang L, Qin B, Shang K, Ding W, Wang J, Cui S
Nat Commun (2024) 15 pp. 4176-4176 [ Pubmed: 38755176 DOI: doi:10.1038/s41467-024-48504-w ]
- Actin-histidine n-methyltransferase (67 kDa, Protein from Homo sapiens)
- 2a protein (fragment) (16 kDa, Protein from Enterovirus A71)
- Zinc ion (65 Da, Ligand)
- Enterovirus protease in complex host factor (Complex from Enterovirus A71)
Structure of a class A GPCR/Fab complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8tlm
Q-score: 0.527
Sun D, Sun Y, Janezic E, Zhou T, Johnson M, Azumaya C, Noreng S, Chiu C, Seki A, Arenzana TL, Nicoludis JM, Shi Y, Wang B, Ho H, Joshi P, Tam C, Payandeh J, Comps-Agrar L, Wang J, Rutz S, Koerber JT, Masureel M
Nat Commun (2023) 14 pp. 7940-7940 [ DOI: doi:10.1038/s41467-023-43601-8 Pubmed: 38040762 ]
- Fab heavy chain (23 kDa, Protein from Oryctolagus cuniculus)
- Ccr8_fab complex (Complex from Homo sapiens)
- Fab light chain (23 kDa, Protein from Oryctolagus cuniculus)
- C-c chemokine receptor type 8, green fluorescent protein fusion (76 kDa, Protein from Aequorea victoria)