pP1192R-DNA-m-AMSA complex DNA binding/cleavage domain
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8yge
Q-score: 0.513
Liu R, Sun J, Li LF, Cheng Y, Li M, Fu L, Li S, Peng G, Wang Y, Liu S, Qu X, Ran J, Li X, Pang E, Qiu HJ, Wang Y, Qi J, Wang H, Gao GF
Nucleic Acids Res (2024) 52 pp. 11301-11316 [ Pubmed: 39166497 DOI: doi:10.1093/nar/gkae703 ]
- Dna (12-mer) (3 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna topoisomerase 2 (135 kDa, Protein from African swine fever virus pig/Kenya/KEN-50/1950)
- Magnesium ion (24 Da, Ligand)
- N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide (393 Da, Ligand)
- Dna (8-mer) (2 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna (20-mer) (6 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Pp1192r-dna-m-amsa complex dna binding/cleavage domain (Complex from African swine fever virus pig/Kenya/KEN-50/1950)
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8ygg
Q-score: 0.475
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8ygh
Q-score: 0.491
Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8y7x
Q-score: 0.331
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Spike glycoprotein (141 kDa, Protein from Human coronavirus HKU1 (isolate N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8y7y
Q-score: 0.577
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Methyl 9-o-acetyl-5-acetamido-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid (365 Da, Ligand)
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Human coronavirus HKU1 (isolate N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8y87
Q-score: 0.355
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1 (isolate N5))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Hku1b-tmprss2 complex (Complex from Human coronavirus HKU1)
Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8y88
Q-score: 0.37
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 2TMPRSS2
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8y89
Q-score: 0.296
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hku1c-tmprss2 complex (Complex from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1)