Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7eoq
Q-score: 0.288
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Structure of the human glun1/glun2a nmda receptor in the glycine/cpp bound state (Complex from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901 bound state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7eor
Q-score: 0.284
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901 bound state (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate bound state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7eos
Q-score: 0.306
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ DOI: doi:10.1016/j.neuron.2021.05.031 Pubmed: 34186027 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate bound state (Complex from Homo sapiens)
Structure of the human GluN1/GluN2A NMDA receptor in the CGP-78608/glutamate bound state
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7eot
Q-score: 0.281
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- Structure of the human glun1/glun2a nmda receptor in the cgp-78608/glutamate bound state (Complex from Homo sapiens)
- [(1s)-1-[[7-bromanyl-2,3-bis(oxidanylidene)-1,4-dihydroquinoxalin-5-yl]methylamino]ethyl]phosphonic acid (378 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901/9-AA bound state
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7eou
Q-score: 0.259
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S
Neuron (2021) 109 pp. 2443-2456.e5 [ Pubmed: 34186027 DOI: doi:10.1016/j.neuron.2021.05.031 ]
- Glutamate receptor ionotropic, nmda 2a (95 kDa, Protein from Homo sapiens)
- 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{r},2~{r})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one (360 Da, Ligand)
- 9-aminoacridine (195 Da, Ligand)
- Structure of the human glun1/glun2a nmda receptor in the glycine/glutamate/gne-6901/9-aa bound state (Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)