Aplysia californica FaNaC in apo state
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7yvc
Q-score: 0.532
Liu F, Dang Y, Li L, Feng H, Li J, Wang H, Zhang X, Zhang Z, Ye S, Tian Y, Chen Q
Nat Chem Biol (2023) 19 pp. 1276-1285 [ DOI: doi:10.1038/s41589-023-01401-7 Pubmed: 37550431 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Trimeric fmrfamide activated sodium channel from aplysia californica (acfanac) (73 kDa, Complex from Aplysia californica)
- Fmrfamide-gated na+ channel (76 kDa, Protein from Aplysia californica)
Modified BG505 SOSIP-based immunogen RC1 in complex with elicited mAb Ab283MUR Fab and 8ANC195 Fab
Escolano A, Gristick HB, Gautam R, DeLaitsch AT, Abernathy ME, Yang Z, Wang H, Hoffmann MAG, Nishimura Y, Wang Z, Koranda N, Kakutani LM, Gao H, Gnanapragasam PNP, Raina H, Gazumyan A, Cipolla M, Oliveira TY, Ramos V, Irvine DJ, Silva M, West Jr AP, Keeffe JR, Barnes CO, Seaman MS, Nussenzweig MC, Martin MA, Bjorkman PJ
Sci Transl Med (2021) 13 pp. eabk1533-eabk1533 [ DOI: doi:10.1126/scitranslmed.abk1533 Pubmed: 34818054 ]
- 8anc195 fab (Complex from Homo sapiens)
- Rc1 sosip (Complex from Human immunodeficiency virus 1)
- Elicited ab283mur fab in complex with rc1 sosip and bnab 8anc195 fab (600 kDa, Complex)
- Ab283mur fab (Complex from Mus musculus)
Modified BG505 SOSIP-based immunogen RC1 in complex with elicited mAb Ab1170NHP Fab and 8ANC195 Fab
Escolano A, Gristick HB, Gautam R, DeLaitsch AT, Abernathy ME, Yang Z, Wang H, Hoffmann MAG, Nishimura Y, Wang Z, Koranda N, Kakutani LM, Gao H, Gnanapragasam PNP, Raina H, Gazumyan A, Cipolla M, Oliveira TY, Ramos V, Irvine DJ, Silva M, West Jr AP, Keeffe JR, Barnes CO, Seaman MS, Nussenzweig MC, Martin MA, Bjorkman PJ
Sci Transl Med (2021) 13 pp. eabk1533-eabk1533 [ DOI: doi:10.1126/scitranslmed.abk1533 Pubmed: 34818054 ]
Resolution: 5.91 Å
EM Method: Single-particle
Fitted PDBs: 6tmw
Q-score: 0.173
Bracher A, Paul SS, Wang H, Wischnewski N, Hartl FU, Hayer-Hartl M
PLoS One (2020) 15 pp. e0230090-e0230090 [ Pubmed: 32339190 DOI: doi:10.1371/journal.pone.0230090 ]
Resolution: 5.8 Å
EM Method: Single-particle
Fitted PDBs: 6tmx
Q-score: 0.163
Bracher A, Paul SS, Wang H, Wischnewski N, Hartl FU, Hayer-Hartl M
PLoS One (2020) 15 pp. e0230090-e0230090 [ Pubmed: 32339190 DOI: doi:10.1371/journal.pone.0230090 ]
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Putative groel-like chaperonine protein (61 kDa, Protein from Pseudomonas phage EL)
- The chaperonin gp146 from the bacteriophage el (pseudomonas aeruginosa) in complex with atpgammas (864 kDa, Complex from Pseudomonas phage EL)
- Magnesium ion (24 Da, Ligand)
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
Resolution: 4.05 Å
EM Method: Single-particle
Fitted PDBs: 6orn
Q-score: 0.423
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West Jr AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC
Nature (2019) 570 pp. 468-473 [ Pubmed: 31142836 DOI: doi:10.1038/s41586-019-1250-z ]
- Complex of rc1 variant of bg505 sosip.664 trimer with three 10-1074 fabs and three cd4bs fabs (600 kDa, Complex from Human immunodeficiency virus 1)
- Rc1 variant of hiv-1 env glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rc1 variant of bg505 sosip.664 trimer (Complex from Human immunodeficiency virus 1)
- 10-1074 antibody fab light chain (23 kDa, Protein from Homo sapiens)
- 10-1074 antibody fab heavy chain (25 kDa, Protein from Homo sapiens)
- Rc1 variant of hiv-1 env glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- 10-1074 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6oro
Q-score: 0.465
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West Jr AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC
Nature (2019) 570 pp. 468-473 [ DOI: doi:10.1038/s41586-019-1250-z Pubmed: 31142836 ]
- Rc1 variant of bg505 sosip.664 trimer (Complex from Human immunodeficiency virus 1)
- Rc1 variant of hiv-1 env glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Rc1 variant of hiv-1 env glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Ab874nhp antibody fab light chain (24 kDa, Protein from Macaca mulatta)
- Ab874nhp antibody fab heavy chain (26 kDa, Protein from Macaca mulatta)
- Complex of rc1 variant of bg505 sosip.664 trimer with three elicted ab874nhp fabs and three human bnab 8anc195 fabs (150 kDa, Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ab874nhp fab (Complex from Macaca mulatta)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6orp
Q-score: 0.358
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West Jr AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC
Nature (2019) 570 pp. 468-473 [ Pubmed: 31142836 DOI: doi:10.1038/s41586-019-1250-z ]
- Rc1 variant of hiv-1 env glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rc1 variant of bg505 sosip.664 trimer (Complex from Human immunodeficiency virus 1)
- Complex of rc1 variant of bg505 sosip.664 trimer with three ab897nhp fabs and three 8anc195 fabs (600 kDa, Complex from Human immunodeficiency virus 1)
- Ab897nhp antibody fab heavy chain (26 kDa, Protein from Macaca mulatta)
- Rc1 variant of hiv-1 env glycoprotein gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Ab897nhp fab (Complex from Macaca mulatta)
- Ab897nhp antibody fab light chain (24 kDa, Protein from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6orq
Q-score: 0.381
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West Jr AP, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC
Nature (2019) 570 pp. 468-473 [ DOI: doi:10.1038/s41586-019-1250-z Pubmed: 31142836 ]
- Rc1 variant of bg505 sosip.664 trimer (Complex from Human immunodeficiency virus 1)
- Ab275mur antibody fab light chain (23 kDa, Protein from Mus musculus)
- Rc1 variant of hiv-1 env glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Ab275mur fab (Complex from Mus musculoides)
- Rc1 variant of hiv-1 env glycoprotein gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of rc1 variant of bg505 sosip.664 trimer with three ab275mur fabs and three 8anc195 fabs (600 kDa, Complex from Human immunodeficiency virus 1)
- Ab275mur antibody fab heavy chain (13 kDa, Protein from Mus musculus)