Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8y7x
Q-score: 0.331
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Spike glycoprotein (141 kDa, Protein from Human coronavirus HKU1 (isolate N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8y7y
Q-score: 0.577
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Methyl 9-o-acetyl-5-acetamido-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid (365 Da, Ligand)
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Human coronavirus HKU1 (isolate N1))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of HCoV-HKU1C spike in the functionally anchored-1up conformation with 1TMPRSS2
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 8y87
Q-score: 0.355
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Hku1b-tmprss2 complex (Complex from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1 (isolate N5))
Structure of HCoV-HKU1C spike in the functionally anchored-2up conformation with 2TMPRSS2
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8y88
Q-score: 0.37
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Hku1a-tmprss2 complex (Complex from Human coronavirus HKU1)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 2TMPRSS2
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8y89
Q-score: 0.296
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hku1c-tmprss2 complex (Complex from Human coronavirus HKU1)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1)
Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 3TMPRSS2
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8y8a
Q-score: 0.308
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1 (isolate N5))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Hku1b-tmprss2 complex (Complex from Human coronavirus HKU1)
Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8y8b
Q-score: 0.597
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- Hku1c-tmprss2 complex (Complex from Human coronavirus HKU1)
- Methyl 9-o-acetyl-5-acetamido-3,5-dideoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid (365 Da, Ligand)
- Transmembrane protease serine 2 (42 kDa, Protein from Homo sapiens)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1 (isolate N5))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7cyp
Q-score: 0.345
Zhu L, Deng YQ, Zhang RR, Cui Z, Sun CY, Fan CF, Xing X, Huang W, Chen Q, Zhang NN, Ye Q, Cao TS, Wang N, Wang L, Cao L, Wang H, Kong D, Ma J, Luo C, Zhang Y, Nie J, Sun Y, Lv Z, Shaw N, Li Q, Li XF, Hu J, Xie L, Rao Z, Wang Y, Wang X, Qin CF
Natl Sci Rev (2021) 8 pp. nwaa297-nwaa297 [ Pubmed: 34676096 DOI: doi:10.1093/nsr/nwaa297 ]
- Light chain of hb27 (11 kDa, Protein from Homo sapiens)
- Hb27 antibody (Complex from Homo sapiens)
- Sars-cov-2 spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike trimer with its neutralizing antibody hb27 (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 spike trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of hb27 (12 kDa, Protein from Homo sapiens)