Architecture of a SARS-CoV-2 mini replication and transcription complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7cxm
Q-score: 0.461
Yan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z, Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z
Nat Commun (2020) 11 pp. 5874-5874 [ DOI: doi:10.1038/s41467-020-19770-1 Pubmed: 33208736 ]
- Rna (Complex from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (25-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Nsp12-nsp7-nsp8-nsp13-rna (Complex)
- Rna (5'-r(p*up*up*up*up*up*u)-3') (1 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (26-mer) (18 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Nsp12-nsp7-nsp8-nsp13 (Complex from Severe acute respiratory syndrome coronavirus 2)
Architecture of a SARS-CoV-2 mini replication and transcription complex
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 7cxn
Q-score: 0.367
Yan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z, Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z
Nat Commun (2020) 11 pp. 5874-5874 [ Pubmed: 33208736 DOI: doi:10.1038/s41467-020-19770-1 ]
- Rna (Complex from Severe acute respiratory syndrome coronavirus 2)
- Primer rna (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Nsp7, nsp8, nsp12, nsp13 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna-directed rna polymerase (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Template rna (18 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(p*up*up*up*up*up*u)-3') (1 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Nsp7, nsp8, nsp12, nsp13 and rna (Complex)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors in reduced conditions
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 7btf
Q-score: 0.569
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z
Science (2020) 368 pp. 779-782 [ Pubmed: 32277040 DOI: doi:10.1126/science.abb7498 ]
- Rna-directed rna polymerase (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Structure of sars-cov-2 rna-dependent rna polymerase in complex with cofactors in reduced condition (155 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Anthrax Toxin Receptor 1-bound spent particles of Seneca Valley Virus in acidic conditions
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 6adl
Q-score: -0.025
Cao L, Zhang R, Liu T, Sun Z, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P, Lou Z, Rao Z
PNAS (2018) 115 pp. 13087-13092 [ Pubmed: 30514821 DOI: doi:10.1073/pnas.1814309115 ]
- Vp1 (25 kDa, Protein from Senecavirus A)
- Vp3 (26 kDa, Protein from Senecavirus A)
- Anthrax toxin receptor 1 (21 kDa, Protein from Homo sapiens)
- Vp2 (27 kDa, Protein from Senecavirus A)
- Magnesium ion (24 Da, Ligand)
- Seneca valley virus (Virus from Seneca valley virus)
Anthrax Toxin Receptor 1-bound full particles of Seneca Valley Virus in acidic conditions
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 6adm
Q-score: -0.027
Cao L, Zhang R, Liu T, Sun Z, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P, Lou Z, Rao Z
PNAS (2018) 115 pp. 13087-13092 [ DOI: doi:10.1073/pnas.1814309115 Pubmed: 30514821 ]
- Vp2 (29 kDa, Protein from Seneca valley virus)
- Vp1 (28 kDa, Protein from Seneca valley virus)
- Seneca valley virus (Virus from Seneca valley virus)
- Vp4 (5 kDa, Protein from Seneca valley virus)
- Magnesium ion (24 Da, Ligand)
- Vp3 (26 kDa, Protein from Seneca valley virus)
- Anthrax toxin receptor 1 (21 kDa, Protein from Homo sapiens)
Anthrax Toxin Receptor 1-bound the Seneca Valley Virus in neutral conditions
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 6adr
Q-score: -0.016
Cao L, Zhang R, Liu T, Sun Z, Hu M, Sun Y, Cheng L, Guo Y, Fu S, Hu J, Li X, Yu C, Wang H, Chen H, Li X, Fry EE, Stuart DI, Qian P, Lou Z, Rao Z
PNAS (2018) 115 pp. 13087-13092 [ DOI: doi:10.1073/pnas.1814309115 Pubmed: 30514821 ]
- Water (18 Da, Ligand)
- Vp1 (28 kDa, Protein from Seneca valley virus)
- Vp2 (29 kDa, Protein from Seneca valley virus)
- Vp4 (7 kDa, Protein from Seneca valley virus)
- Vp3 (26 kDa, Protein from Seneca valley virus)
- Seneca valley virus (Virus from Seneca valley virus)
- Magnesium ion (24 Da, Ligand)
- Anthrax toxin receptor 1 (21 kDa, Protein from Homo sapiens)