Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 9jmz
Q-score: 0.489
Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang Y, Chen J, Li Y, Jin X, Duan X, Zhang W, Bi Y, Jin R, Sun L, Wang N, Gao GF
Cell (2025) [ Pubmed: 39848246 DOI: doi:10.1016/j.cell.2025.01.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Human-infecting bovine influenza h5n1 hemagglutinin complexed with avian receptor analog lsta (Complex from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Indonesia/5/2005(H5N1)))
Cryo-EM structure of chitin synthase
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8k52
Q-score: 0.456
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ DOI: doi:10.3390/ijms252111667 Pubmed: 39519219 ]
- Manganese (ii) ion (54 Da, Ligand)
- Uridine-5'-diphosphate (404 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae)
Cryo-EM structure of chitin synthase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8z0o
Q-score: 0.486
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Manganese (ii) ion (54 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae strain P6497)
- Uridine-5'-diphosphate (404 Da, Ligand)
Yeast RAVE bound to V-ATPase V1 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9cop
Q-score: 0.252
Wang H, Tarsio M, Kane PM, Rubinstein JL
PNAS (2024) 121 pp. e2414511121-e2414511121 [ Pubmed: 39625975 DOI: doi:10.1073/pnas.2414511121 ]
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae)
- Regulator of v-atpase in vacuolar membrane protein 2 (40 kDa, Protein from Saccharomyces cerevisiae)
- Suppressor of kinetochore protein 1 (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit h (54 kDa, Protein from Saccharomyces cerevisiae)
- Regulator of v-atpase in vacuolar membrane protein 1 (155 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit g (12 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase catalytic subunit a (118 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Yeast rave bound to v-atpase v1 complex (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit b (57 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 9chu
Q-score: 0.478
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
- Noradrenaline (170 Da, Ligand)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (49 kDa, Protein from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
pP1192R-DNA-m-AMSA complex DNA binding/cleavage domain
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8yge
Q-score: 0.513
Liu R, Sun J, Li LF, Cheng Y, Li M, Fu L, Li S, Peng G, Wang Y, Liu S, Qu X, Ran J, Li X, Pang E, Qiu HJ, Wang Y, Qi J, Wang H, Gao GF
Nucleic Acids Res (2024) 52 pp. 11301-11316 [ Pubmed: 39166497 DOI: doi:10.1093/nar/gkae703 ]
- Dna (12-mer) (3 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna topoisomerase 2 (135 kDa, Protein from African swine fever virus pig/Kenya/KEN-50/1950)
- Magnesium ion (24 Da, Ligand)
- N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide (393 Da, Ligand)
- Dna (8-mer) (2 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna (20-mer) (6 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Pp1192r-dna-m-amsa complex dna binding/cleavage domain (Complex from African swine fever virus pig/Kenya/KEN-50/1950)
RO76 bound muOR-Gi1-scFv16 complex structure
Ople RS, Ramos-Gonzalez N, Li Q, Sobecks BL, Aydin D, Powers AS, Faouzi A, Polacco BJ, Bernhard SM, Appourchaux K, Sribhashyam S, Eans SO, Tsai BA, Dror RO, Varga BR, Wang H, Huttenhain R, McLaughlin JP, Majumdar S
ACS Cent Sci (2024) 10 pp. 1490-1503 [ Pubmed: 39220695 DOI: doi:10.1021/acscentsci.4c00525 ]
- Water (18 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- N-{[3-(hydroxymethyl)phenyl]methyl}-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide (380 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Mu-type opioid receptor (39 kDa, Protein from Mus musculus)
- Ro76 bound muor-gi1-scfv16 complex (Complex from Mus musculus)
Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8y65
Q-score: 0.325
Shen Z, Xu L, Wu T, Wang H, Wang Q, Ge X, Kong F, Huang G, Pan X
Nat Commun (2024) 15 pp. 5039-5039 [ DOI: doi:10.1038/s41467-024-49420-9 Pubmed: 38866775 ]
- Glut9 in complex with urate (Complex from Homo sapiens)
- Uric acid (168 Da, Ligand)
- Solute carrier family 2, facilitated glucose transporter member 9 (63 kDa, Protein from Homo sapiens)
Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8w09
Q-score: 0.461
Li M, Yang R, Chen X, Wang H, Ghirlando R, Dimitriadis EK, Craigie R
J Mol Biol (2024) 436 pp. 168557-168557 [ Pubmed: 38582148 DOI: doi:10.1016/j.jmb.2024.168557 ]
- (4r,12as)-n-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2h-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide (419 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Integrase (32 kDa, Protein from Human immunodeficiency virus 1)
- Magnesium ion (24 Da, Ligand)
- Vdna (8 kDa, DNA from Human immunodeficiency virus 1)
- Wild-type hiv-1 intasomes (400 kDa, Complex from Human immunodeficiency virus 1)
- Vdna (27 kDa, DNA from Human immunodeficiency virus 1)