Cryo-EM structure of chitin synthase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8z0o
Q-score: 0.486
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Manganese (ii) ion (54 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae strain P6497)
- Uridine-5'-diphosphate (404 Da, Ligand)
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 9chu
Q-score: 0.478
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
- Noradrenaline (170 Da, Ligand)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (49 kDa, Protein from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in apo state
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 9chv
Q-score: 0.39
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (51 kDa, Protein from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in carazolol bound inactive state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9chx
Q-score: 0.431
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- (2s)-1-(9h-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol (298 Da, Ligand)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (51 kDa, Protein from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
RO76 bound muOR-Gi1-scFv16 complex structure
Ople RS, Ramos-Gonzalez N, Li Q, Sobecks BL, Aydin D, Powers AS, Faouzi A, Polacco BJ, Bernhard SM, Appourchaux K, Sribhashyam S, Eans SO, Tsai BA, Dror RO, Varga BR, Wang H, Huttenhain R, McLaughlin JP, Majumdar S
ACS Cent Sci (2024) 10 pp. 1490-1503 [ Pubmed: 39220695 DOI: doi:10.1021/acscentsci.4c00525 ]
- Water (18 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- N-{[3-(hydroxymethyl)phenyl]methyl}-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide (380 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (27 kDa, Protein from Mus musculus)
- Mu-type opioid receptor (39 kDa, Protein from Mus musculus)
- Ro76 bound muor-gi1-scfv16 complex (Complex from Mus musculus)
Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate
Resolution: 3.51 Å
EM Method: Single-particle
Fitted PDBs: 8y65
Q-score: 0.325
Shen Z, Xu L, Wu T, Wang H, Wang Q, Ge X, Kong F, Huang G, Pan X
Nat Commun (2024) 15 pp. 5039-5039 [ DOI: doi:10.1038/s41467-024-49420-9 Pubmed: 38866775 ]
- Glut9 in complex with urate (Complex from Homo sapiens)
- Uric acid (168 Da, Ligand)
- Solute carrier family 2, facilitated glucose transporter member 9 (63 kDa, Protein from Homo sapiens)
Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin
Fe-O nanocluster of form-X in the 4-fold channel of Ureaplasma diversum ferritin
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wqx
Q-score: 0.541
Wang W, Xi H, Fu D, Ma D, Gong W, Zhao Y, Li X, Wu L, Guo Y, Zhao G, Wang H
J Am Chem Soc (2024) 146 pp. 11657-11668 [ DOI: doi:10.1021/jacs.3c13830 Pubmed: 38641862 ]
- Ferritin (21 kDa, Protein from Ureaplasma diversum)
- Fe (iii) ion (55 Da, Ligand)
- Ferritin (Complex from Ureaplasma diversum)
Fe-O nanocluster of form-XI in the 4-fold channel of Ureaplasma diversum ferritin
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8wqy
Q-score: 0.55
Wang W, Xi H, Fu D, Ma D, Gong W, Zhao Y, Li X, Wu L, Guo Y, Zhao G, Wang H
J Am Chem Soc (2024) 146 pp. 11657-11668 [ DOI: doi:10.1021/jacs.3c13830 Pubmed: 38641862 ]
- Water (18 Da, Ligand)
- Ferritin (21 kDa, Protein from Ureaplasma diversum)
- Fe (iii) ion (55 Da, Ligand)
- Ferritin (Complex from Ureaplasma diversum)
Fe-O nanocluster of form-XII in the 4-fold channel of Ureaplasma diversum ferritin
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wr0
Q-score: 0.54
Wang W, Xi H, Fu D, Ma D, Gong W, Zhao Y, Li X, Wu L, Guo Y, Zhao G, Wang H
J Am Chem Soc (2024) 146 pp. 11657-11668 [ DOI: doi:10.1021/jacs.3c13830 Pubmed: 38641862 ]
- Ferritin (21 kDa, Protein from Ureaplasma diversum)
- Fe (iii) ion (55 Da, Ligand)
- Ferritin (Complex from Ureaplasma diversum)