Langya virus F glycoprotein ectodomain in prefusion form
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8fmx
Q-score: 0.457
Isaacs A, Low YS, Macauslane KL, Seitanidou J, Pegg CL, Cheung STM, Liang B, Scott CAP, Landsberg MJ, Schulz BL, Chappell KJ, Modhiran N, Watterson D
Nat Commun (2023) 14 pp. 3577-3577 [ Pubmed: 37328468 DOI: doi:10.1038/s41467-023-39278-8 ]
- Langya virus f ectodomain in prefusion form (200 kDa, Complex from Langya virus)
- Fusion glycoprotein (52 kDa, Protein from Langya virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Mojiang virus F ectodomain in prefusion form
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8fmy
Q-score: 0.564
Isaacs A, Low YS, Macauslane KL, Seitanidou J, Pegg CL, Cheung STM, Liang B, Scott CAP, Landsberg MJ, Schulz BL, Chappell KJ, Modhiran N, Watterson D
Nat Commun (2023) 14 pp. 3577-3577 [ DOI: doi:10.1038/s41467-023-39278-8 Pubmed: 37328468 ]
- Mojiang virus f glycoprotein ectodomain in the prefusion form (200 kDa, Complex from Mojiang virus)
- Fusion glycoprotein f0 (52 kDa, Protein from Mojiang virus)
Binjari virus (BinJV) complexed with pr-specific Fab 2A7
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Binjari virus complexed with pr-specific fab 2a7 (22 MDa, Complex)
- 2a7 fab (50 kDa, Complex from Mus musculus)
- Binjari virus (22 MDa, Virus from Binjari virus)
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7l30
Q-score: 0.418
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Envelope protein e (53 kDa, Protein from Binjari virus)
- Binjari virus (22 MDa, Virus from Binjari virus)
- Prm protein (18 kDa, Protein from Binjari virus)
Chimeric flavivirus between Binjari virus and Dengue virus serotype-2
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7kv8
Q-score: 0.701
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ DOI: doi:10.1038/s41467-021-22773-1 Pubmed: 34075032 ]
- Water (18 Da, Ligand)
- (2s,3r,4z)-3-hydroxy-2-[(9e)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate (643 Da, Ligand)
- Envelope protein e (54 kDa, Protein from Dengue virus 2)
- M and e from dengue virus serotype-2 isolate et300 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Dengue virus 2)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
Chimeric flavivirus between Binjari virus and West Nile (Kunjin) virus
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7kv9
Q-score: 0.588
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ DOI: doi:10.1038/s41467-021-22773-1 Pubmed: 34075032 ]
- M and e from west nile virus isolate nsw2011 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Kunjin virus)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
Structure of West Nile virus (Kunjin)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7kva
Q-score: 0.555
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ DOI: doi:10.1038/s41467-021-22773-1 Pubmed: 34075032 ]
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Kunjin virus (22 MDa, Virus from Kunjin virus)
- Matrix protein m (8 kDa, Protein from Kunjin virus)
Chimeric flavivirus between Binjari virus and Murray Valley encephalitis virus
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7kvb
Q-score: 0.48
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ DOI: doi:10.1038/s41467-021-22773-1 Pubmed: 34075032 ]
- Envelope protein e (53 kDa, Protein from Murray Valley encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Murray Valley encephalitis virus)
- M and e from murray valley encephalitis virus strain mve-1-51 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Murray Valley encephalitis virus)
Cryo-EM reconstruction of the mature chimeric BinJV/ZIKV-prME virion
Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA
Sci Transl Med (2019) 11 [ Pubmed: 31826984 DOI: doi:10.1126/scitranslmed.aax7888 ]
- Zika virus (Virus from Zika virus)
Cryo-EM reconstruction of the mature chimeric BinJV/ZIKV-prME virion in complex with Fab C8
Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA
Sci Transl Med (2019) 11 [ Pubmed: 31826984 DOI: doi:10.1126/scitranslmed.aax7888 ]
- Zika virus (Virus from Zika virus)