The structure of an infectious immature flavivirus redefines viral architecture and maturation
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7l30
Q-score: 0.418
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Envelope protein e (53 kDa, Protein from Binjari virus)
- Prm protein (18 kDa, Protein from Binjari virus)
- Binjari virus (22 MDa, Virus from Binjari virus)
Chimeric flavivirus between Binjari virus and Dengue virus serotype-2
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7kv8
Q-score: 0.701
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Envelope protein e (54 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M and e from dengue virus serotype-2 isolate et300 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Dengue virus 2)
- (2s,3r,4z)-3-hydroxy-2-[(9e)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate (643 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Dengue virus 2)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Water (18 Da, Ligand)
Chimeric flavivirus between Binjari virus and West Nile (Kunjin) virus
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7kv9
Q-score: 0.588
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- Binjari virus (11 MDa, Virus from Binjari virus)
- M and e from west nile virus isolate nsw2011 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Kunjin virus)
Structure of West Nile virus (Kunjin)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7kva
Q-score: 0.555
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Kunjin virus (22 MDa, Virus from Kunjin virus)
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
Chimeric flavivirus between Binjari virus and Murray Valley encephalitis virus
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7kvb
Q-score: 0.48
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Murray Valley encephalitis virus)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Murray Valley encephalitis virus)
- M and e from murray valley encephalitis virus strain mve-1-51 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Murray Valley encephalitis virus)