Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state A)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7px9
Q-score: 0.402
Kavalchuk M, Jomaa A, Muller AU, Weber-Ban E
Nat Commun (2022) 13 pp. 276-276 [ Pubmed: 35022401 DOI: doi:10.1038/s41467-021-27787-3 ]
- Prokaryotic ubiquitin-like protein pup (7 kDa, Protein from Mycobacterium tuberculosis)
- Aaa atpase forming ring-shaped complexes (67 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mycobacterial proteasome-associated atpase in complex with substrate and open-gate 20scp (1 MDa, Complex from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Open-gate mycobacterium 20S CP proteasome in complex MPA - global 3D refinement
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7pxa
Q-score: 0.555
Kavalchuk M, Jomaa A, Muller AU, Weber-Ban E
Nat Commun (2022) 13 pp. 276-276 [ Pubmed: 35022401 DOI: doi:10.1038/s41467-021-27787-3 ]
- Mycobacterial proteasome-associated atpase in complex with substrate and open-gate 20scp (1 MDa, Complex from Mycobacterium tuberculosis)
- Proteasome subunit alpha (26 kDa, Protein from Mycobacterium tuberculosis)
- Aaa atpase forming ring-shaped complexes (67 kDa, Protein from Mycobacterium tuberculosis)
- Proteasome subunit beta (30 kDa, Protein from Mycobacterium tuberculosis)
Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state B)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7pxb
Q-score: 0.35
Kavalchuk M, Jomaa A, Muller AU, Weber-Ban E
Nat Commun (2022) 13 pp. 276-276 [ Pubmed: 35022401 DOI: doi:10.1038/s41467-021-27787-3 ]
- Prokaryotic ubiquitin-like protein pup (7 kDa, Protein from Mycobacterium tuberculosis)
- Aaa atpase forming ring-shaped complexes (67 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mycobacterial proteasome-associated atpase in complex with substrate and open-gate 20scp (1 MDa, Complex from Mycobacterium tuberculosis)
Resolution: 3.84 Å
EM Method: Single-particle
Fitted PDBs: 7pxc
Q-score: 0.474
Kavalchuk M, Jomaa A, Muller AU, Weber-Ban E
Nat Commun (2022) 13 pp. 276-276 [ Pubmed: 35022401 DOI: doi:10.1038/s41467-021-27787-3 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mycobacterial proteasome-associated atpase in complex with substrate and open-gate 20scp (1 MDa, Complex from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Prokaryotic ubiquitin-like protein pup (7 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Proteasome subunit beta (30 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Proteasome subunit alpha (26 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
- Proteasome-associated atpase (67 kDa, Protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv))
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7pxd
Q-score: 0.453
Kavalchuk M, Jomaa A, Muller AU, Weber-Ban E
Nat Commun (2022) 13 pp. 276-276 [ Pubmed: 35022401 DOI: doi:10.1038/s41467-021-27787-3 ]
- Prokaryotic ubiquitin-like protein pup (7 kDa, Protein from Mycobacterium tuberculosis)
- Proteasome subunit alpha (26 kDa, Protein from Mycobacterium tuberculosis)
- Aaa atpase forming ring-shaped complexes (67 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mycobacterial proteasome-associated atpase in complex with substrate and open-gate 20scp (1 MDa, Complex from Mycobacterium tuberculosis)
- Proteasome subunit beta (30 kDa, Protein from Mycobacterium tuberculosis)
Bolten M, Delley CL, Leibundgut M, Boehringer D, Ban N, Weber-Ban E
Structure (2016) 24 pp. 2138-2151 [ Pubmed: 27839949 DOI: doi:10.1016/j.str.2016.10.008 ]
Binding of the C-terminal GQYL motif of the bacterial proteasome activator Bpa to the 20S proteasome
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 5lzp
Q-score: 0.44
Bolten M, Delley CL, Leibundgut M, Boehringer D, Ban N, Weber-Ban E
Structure (2016) 24 pp. 2138-2151 [ Pubmed: 27839949 DOI: doi:10.1016/j.str.2016.10.008 ]
- Proteasome subunit beta (25 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Bacterial proteasome activator (19 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Proteasome subunit alpha (26 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Proteasome in complex with bacterial proteasome activator (930 kDa, Complex from Mycobacterium tuberculosis H37Rv)