Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6pbx
Q-score: 0.351
eLife (2019) 8 [ DOI: doi:10.7554/eLife.49188 Pubmed: 31490124 ]
- Potassium voltage-gated channel subfamily h member 1 (96 kDa, Protein from Rattus norvegicus)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Calmodulin (Complex from Homo sapiens)
- Voltage-gated potassium channel eag1 3-13 deletion mutant bound to calmodulin (Complex)
- Voltage-gated potassium channel eag1 3-13 deletion mutant (Complex from Rattus norvegicus)
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 6pby
Q-score: 0.407
eLife (2019) 8 [ DOI: doi:10.7554/eLife.49188 Pubmed: 31490124 ]
- Potassium voltage-gated channel subfamily h member 1 (96 kDa, Protein from Rattus norvegicus)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Calmodulin (Complex from Homo sapiens)
- Voltage-gated potassium channel eag1 3-13 deletion mutant bound to calmodulin (Complex)
- Voltage-gated potassium channel eag1 3-13 deletion mutant (Complex from Rattus norvegicus)
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 5k7l
Q-score: 0.302
Science (2016) 353 pp. 664-669 [ DOI: doi:10.1126/science.aaf8070 Pubmed: 27516594 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calmodulin (16 kDa, Protein from Homo sapiens)
- Calmodulin (17 kDa, Cellular component from Homo sapiens)
- Voltage-gated potassium channel eag1 (380 kDa, Cellular component from Rattus norvegicus)
- Voltage-gated k+ channel eag1 bound to the channel inhibitor calmodulin (450 kDa, Cellular component)
- Potassium voltage-gated channel subfamily h member 1 (97 kDa, Protein from Rattus norvegicus)
- Cholesterol hemisuccinate (486 Da, Ligand)
Cryo-EM structure of holo-PikAIII conformation 1
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of holo-PikAIII conformation 2
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of PikAIII/delta ACP5
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure pentaketide-ACP4-PikAIII/C209A/delta ACP5
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
- Pentaketide (Ligand from unidentified)
- Pikaiii (348 kDa, Protein from Streptomyces venezuelae)
- Pentaketide-acp4-pikaiii/c209a/delta acp5 (348 kDa, Sample)
Cryo-EM structure of MeMal-PikAIII
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
- Memal-pikaiii (328 kDa, Sample)
- Pikaiii (328 kDa, Protein from Streptomyces venezuelae)
holo-ACP4-PikAIII/C209A/delta ACP5 (no pentaketide)
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of Pentaketide-KS5-PikAIII
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 560-564 [ DOI: doi:10.1038/nature13409 Pubmed: 24965656 ]