Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation.
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7y1j
Q-score: 0.58
Ding D, Hou T, Wei M, Wu JX, Chen L
Nat Commun (2023) 14 pp. 3608-3608 [ DOI: doi:10.1038/s41467-023-39379-4 Pubmed: 37330603 ]
- Repaglinide (452 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Atp-binding cassette sub-family c member 9, isoform a (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7y1k
Q-score: 0.413
Ding D, Hou T, Wei M, Wu JX, Chen L
Nat Commun (2023) 14 pp. 3608-3608 [ DOI: doi:10.1038/s41467-023-39379-4 Pubmed: 37330603 ]
- Repaglinide (452 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Atp-binding cassette sub-family c member 9, isoform a (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2B in complex with Mg-ATP and repaglinide in the inward-facing conformation
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 7y1l
Q-score: 0.424
Ding D, Hou T, Wei M, Wu JX, Chen L
Nat Commun (2023) 14 pp. 3608-3608 [ DOI: doi:10.1038/s41467-023-39379-4 Pubmed: 37330603 ]
- Repaglinide (452 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 7y1m
Q-score: 0.467
Ding D, Hou T, Wei M, Wu JX, Chen L
Nat Commun (2023) 14 pp. 3608-3608 [ DOI: doi:10.1038/s41467-023-39379-4 Pubmed: 37330603 ]
- Repaglinide (452 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 7y1n
Q-score: 0.466
Ding D, Hou T, Wei M, Wu JX, Chen L
Nat Commun (2023) 14 pp. 3608-3608 [ DOI: doi:10.1038/s41467-023-39379-4 Pubmed: 37330603 ]
- Repaglinide (452 Da, Ligand)
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2B in complex with Mg-ATP/ADP
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7vlr
Q-score: 0.468
Ding D, Wu JX, Duan X, Ma S, Lai L, Chen L
Nat Commun (2022) 13 pp. 2675-2675 [ DOI: doi:10.1038/s41467-022-30428-y Pubmed: 35562524 ]
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
Structure of SUR2B in complex with MgATP/ADP and P1075
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7vls
Q-score: 0.494
Ding D, Wu JX, Duan X, Ma S, Lai L, Chen L
Nat Commun (2022) 13 pp. 2675-2675 [ DOI: doi:10.1038/s41467-022-30428-y Pubmed: 35562524 ]
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
- 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine (231 Da, Ligand)
Structure of SUR2B in complex with Mg-ATP/ADP and levcromakalim
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7vlt
Q-score: 0.52
Ding D, Wu JX, Duan X, Ma S, Lai L, Chen L
Nat Commun (2022) 13 pp. 2675-2675 [ DOI: doi:10.1038/s41467-022-30428-y Pubmed: 35562524 ]
- Isoform sur2b of atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- (3s,4r)-2,2-dimethyl-3-oxidanyl-4-(2-oxidanylidenepyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile (286 Da, Ligand)
- Atp-binding cassette sub-family c member 9, isoform b (174 MDa, Complex from Rattus norvegicus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Structure of SUR2A in complex with Mg-ATP/ADP and P1075
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7vlu
Q-score: 0.487
Ding D, Wu JX, Duan X, Ma S, Lai L, Chen L
Nat Commun (2022) 13 pp. 2675-2675 [ DOI: doi:10.1038/s41467-022-30428-y Pubmed: 35562524 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Atp-binding cassette sub-family c member 9 (174 kDa, Protein from Rattus norvegicus)
- Atp-binding cassette sub-family c member 9, isoform a (174 MDa, Complex from Rattus norvegicus)
- 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine (231 Da, Ligand)
Structure of human TRPC5 in complex with clemizole
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7d4p
Q-score: 0.563
Song K, Wei M, Guo W, Quan L, Kang Y, Wu JX, Chen L
eLife (2021) 10 [ DOI: doi:10.7554/eLife.63429 Pubmed: 33683200 ]
- (2s)-2-(hexadecanoyloxy)-3-hydroxypropyl (9z)-octadec-9-enoate (594 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Human transient receptor potential channel 5 tetramer (Complex from Homo sapiens)
- Phosphatidylethanolamine (734 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Short transient receptor potential channel 5 (88 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole (325 Da, Ligand)