Cryo-EM density map of EBV gHgL-gp42 in complex with four mAbs 5E3, 3E8, 6H2 and 10E4
Hong J, Zhong L, Liu L, Wu Q, Zhang W, Chen K, Wei D, Sun H, Zhou X, Zhang X, Kang YF, Huang Y, Chen J, Wang G, Zhou Y, Chen Y, Feng QS, Yu H, Li S, Zeng MS, Zeng YX, Xu M, Zheng Q, Chen Y, Zhang X, Xia N
Cell Rep Med (2023) 4 pp. 101296-101296 [ Pubmed: 37992686 DOI: doi:10.1016/j.xcrm.2023.101296 ]
Cryo-EM maps of the (TGA3)2-(NPR1)2-(TGA3)2 complex
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
cryo-EM maps of the (NPR1)2-(TGA3)2 complex
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7mk2
Q-score: 0.453
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
- Zinc ion (65 Da, Ligand)
- Regulatory protein npr1 (67 kDa, Protein from Arabidopsis thaliana)
- Npr1 dimer (Complex from Arabidopsis thaliana)
CryoEM Map of the NPR1-SA complex
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7tac
Q-score: 0.329
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
- Zinc ion (65 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Regulatory protein npr1 (67 kDa, Protein from Arabidopsis thaliana)
- (tga3)2-(npr1)2-(tga3)2 complex (Complex from Arabidopsis thaliana)
- Transcription factor tga3 (36 kDa, Protein from Arabidopsis thaliana)
CryoEM structure of the (NPR1)2-(TGA3)2 complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7tad
Q-score: 0.357
Kumar S, Zavaliev R, Wu Q, Zhou Y, Cheng J, Dillard L, Powers J, Withers J, Zhao J, Guan Z, Borgnia MJ, Bartesaghi A, Dong X, Zhou P
Nature (2022) 605 pp. 561-566 [ Pubmed: 35545668 DOI: doi:10.1038/s41586-022-04699-w ]
- Zinc ion (65 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Regulatory protein npr1 (67 kDa, Protein from Arabidopsis thaliana)
- (npr1)2-(tga3)2 complex (Complex from Arabidopsis thaliana)
- Transcription factor tga3 (36 kDa, Protein from Arabidopsis thaliana)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6kzo
Q-score: 0.508
Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N
Nature (2019) 576 pp. 492-497 [ Pubmed: 31766050 DOI: doi:10.1038/s41586-019-1801-3 ]
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane protein (Complex from Homo sapiens)
- Voltage-dependent t-type calcium channel subunit alpha-1g (250 kDa, Protein from Homo sapiens)
- Cholesterol hemisuccinate (486 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6kzp
Q-score: 0.548
Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N
Nature (2019) 576 pp. 492-497 [ Pubmed: 31766050 DOI: doi:10.1038/s41586-019-1801-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Voltage-dependent t-type calcium channel subunit alpha-1g,voltage-dependent t-type calcium channel subunit alpha-1g (238 kDa, Protein from Homo sapiens)
- Membrane protein-ligand (Complex from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- ~{n}-[[1-[2-(~{tert}-butylamino)-2-oxidanylidene-ethyl]piperidin-4-yl]methyl]-3-chloranyl-5-fluoranyl-benzamide (383 Da, Ligand)
Rabbit Cav1.1-Nifedipine Complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6jp5
Q-score: 0.39
Zhao Y, Huang G, Wu J, Wu Q, Gao S, Yan Z, Lei J, Yan N
Cell (2019) 177 pp. 1495-1506.e12 [ DOI: doi:10.1016/j.cell.2019.04.043 Pubmed: 31150622 ]
- Voltage-dependent l-type calcium channel subunit beta-1 (49 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (346 Da, Ligand)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (121 kDa, Protein from Oryctolagus cuniculus)
- Cav1.1-drug complex (Complex)
- Cav1.1-beta1a-alpha2-delta1-gamma complex (Complex from Oryctolagus cuniculus)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- Ethanolamine (61 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)