Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
- Alpha-d-mannopyranose (180 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xoe
Q-score: 0.301
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
The conformation C1-3 for the ectodomain of the full-length human insulin receptor in apo.
Yu D, Zhang X, Sun J, Li X, Wu Z, Han X, Fan C, Ma Y, Ouyang Q, Wang T
To Be Published
- Human insulin receptor (Protein from Homo sapiens)
- Human insulin receptor (130 kDa, Complex from Homo sapiens)
The conformation C4 for the ectodomain of the full-length human insulin receptor in apo.
Yu D, Zhang X, Sun J, Li X, Wu Z, Han X, Fan C, Ma Y, Ouyang Q, Wang T
To Be Published
- Human insulin receptor (Protein from Homo sapiens)
- Human insulin receptor (130 kDa, Complex from Homo sapiens)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7bw7
Q-score: 0.333
Yu D, Zhang X, Sun J, Li X, Wu Z, Han X, Fan C, Ma Y, Ouyang Q, Wang T
To Be Published
- Insulin receptor (Complex from Homo sapiens)
- Insulin (Complex)
- Insulin fusion (8 kDa, Protein from Homo sapiens)
- Human insulin receptor complexed with 1 insulin (130 kDa, Complex from Homo sapiens)
- Insulin receptor (154 kDa, Protein from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bw8
Q-score: 0.353
Yu D, Zhang X, Sun J, Li X, Wu Z, Han X, Fan C, Ma Y, Ouyang Q, Wang T
To Be Published
- Insulin fusion (8 kDa, Protein from Homo sapiens)
- Human insulin receptor complexed with 1 insulin (130 kDa, Complex from Homo sapiens)
- Insulin (Complex)
- Insulin receptor (Complex from Homo sapiens)
- Insulin receptor (154 kDa, Protein from Homo sapiens)
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 7bwa
Q-score: 0.183
Yu D, Zhang X, Sun J, Li X, Wu Z, Han X, Fan C, Ma Y, Ouyang Q, Wang T
To Be Published
- Insulin fusion (8 kDa, Protein from Homo sapiens)
- Insulin receptor (Complex from Homo sapiens)
- Human insulin receptor complexed with 1 insulin (130 kDa, Complex from Homo sapiens)
- Insulin (Complex)
- Insulin receptor (154 kDa, Protein from Homo sapiens)
cryoEM 3D reconstruction of IGF1R in complex with IGF1
Zhang X, Yu D, Sun J, Wu Y, Gong J, Li X, Liu L, Liu S, Liu J, Wu Y, Li D, Ma Y, Han X, Zhu Y, Wu Z, Wang Y, Ouyang Q, Wang T
Structure (2020) 28 pp. 555-561.e4 [ DOI: doi:10.1016/j.str.2020.03.007 Pubmed: 32275863 ]
- Igf1 receptor (Protein from Homo sapiens)
- Igf1r (300 MDa, Complex from Homo sapiens)
Cryo-EM structure of the full-length human IGF-1R in complex with insulin
Resolution: 5.0 Å
EM Method: Single-particle
Fitted PDBs: 6jk8
Q-score: 0.122
Zhang X, Yu D, Sun J, Wu Y, Gong J, Li X, Liu L, Liu S, Liu J, Wu Y, Li D, Ma Y, Han X, Zhu Y, Wu Z, Wang Y, Ouyang Q, Wang T
Structure (2020) 28 pp. 555-561.e4 [ Pubmed: 32275863 DOI: doi:10.1016/j.str.2020.03.007 ]
- Insulin (11 kDa, Protein from Homo sapiens)
- Complex of full-length human type 1 insulin-like growth factor receptor with insulin (310 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Insulin-like growth factor 1 receptor (154 kDa, Protein from Homo sapiens)