Structure of the post state human RNA Polymerase I Elongation Complex
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7vbb
Q-score: 0.401
Zhao D, Liu W, Chen K, Wu Z, Yang H, Xu Y
Cell Discov (2021) 7 pp. 97-97 [ Pubmed: 34671025 DOI: doi:10.1038/s41421-021-00335-5 ]
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*gp*cp*up*gp*ap*cp*u)-3') (2 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna (5'-d(*cp*tp*gp*tp*cp*cp*tp*cp*tp*gp*gp*cp*gp*a)-3') (4 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (194 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Post state of human rna polymerase i elongation complex (Complex from Homo sapiens)
- Dna (25-mer) (7 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Homo sapiens)
Structure of the pre state human RNA Polymerase I Elongation Complex
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7vba
Q-score: 0.525
Zhao D, Liu W, Chen K, Wu Z, Yang H, Xu Y
Cell Discov (2021) 7 pp. 97-97 [ Pubmed: 34671025 DOI: doi:10.1038/s41421-021-00335-5 ]
- Dna-directed rna polymerase i subunit rpa2 (128 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- 5'-o-[(s)-hydroxy{[(s)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine (481 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa49 (47 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa34 (55 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*gp*cp*up*gp*ap*cp*u)-3') (2 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna (5'-d(p*gp*cp*cp*ap*gp*ap*gp*ap*cp*ap*gp*cp*gp*ap*gp*tp*cp*ap*gp*cp*ap*a)-3') (6 kDa, DNA from Homo sapiens)
- Human rna polymerase i elongation complex (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna (5'-d(p*a*cp*tp*gp*tp*cp*cp*tp*cp*tp*gp*gp*c)-3') (3 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa1 (194 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase i subunit rpa12 (13 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase i subunit rpa43 (37 kDa, Protein from Homo sapiens)
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7egg
Q-score: 0.56
Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y
Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
- Tfiid lobe b subcomplex (Complex from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
