Cryo-EM structure of NRG1A(LRR) in complex with EDS1-SAG101-(ADPr-ATP)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8yn1
Q-score: 0.561
Huang S, Wang J, Song R, Jia A, Xiao Y, Sun Y, Wang L, Mahr D, Wu Z, Han Z, Li X, Parker JE, Chai J
Nature (2025) [ Pubmed: 39939760 DOI: doi:10.1038/s41586-024-08521-7 ]
- Probable disease resistance protein at5g66900 (46 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Senescence-associated carboxylesterase 101 (61 kDa, Protein from Arabidopsis thaliana)
- Ternary complex of nrg1a(lrr) with eds1-sag101-(adpr-atp) (Complex from Arabidopsis)
- Protein eds1 (70 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of P97-VCPIP1 complex
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8yka
Q-score: 0.366
Liao T, Li R, Lu P, Liu Y, Yang R, Guo H, Wu Z, Wang R, Yuan L, Hu Z, Gao H, Li F
Adv Sci (2024) 11 pp. e2403417-e2403417 [ Pubmed: 39234822 DOI: doi:10.1002/advs.202403417 ]
- Transitional endoplasmic reticulum atpase (85 kDa, Protein from Homo sapiens)
- P97-vcpip1 complex (Complex from Homo sapiens)
- Deubiquitinating protein vcpip1 (63 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ DOI: doi:10.1016/j.scib.2023.11.024 Pubmed: 37993332 ]
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- Alpha-d-mannopyranose (180 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xoe
Q-score: 0.301
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ DOI: doi:10.1016/j.scib.2023.11.024 Pubmed: 37993332 ]
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz4
Q-score: 0.368
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-3 fab light chain (23 kDa, Protein from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-3 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-3 fab vh and vl domains (Complex from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-3 fab heavy chain (25 kDa, Protein from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7uz5
Q-score: 0.355
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p in complex with m8a-6 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-6 fab vh and vl domains (Complex from Mus musculus)
- M8a-6 fab light chain (23 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-6 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-6 fab heavy chain (25 kDa, Protein from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-28
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uz6
Q-score: 0.477
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p in complex with m8a-28 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-28 fab light chain (23 kDa, Protein from Mus musculus)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-28 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-28 fab heavy chain (25 kDa, Protein from Mus musculus)
- M8a-28 fab vh and vl domains (Complex from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7uz7
Q-score: 0.36
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uz8
Q-score: 0.35
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-31 fab vh and vl domains (Complex from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 omicron spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-31 fab ch1 and cl domains (Complex from Mus musculus)
- M8a-31 fab light chain (24 kDa, Protein from Mus musculus)
- Sars-cov-2 omicron ba.1 s 6p in complex with m8a-31 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-31 fab heavy chain (24 kDa, Protein from Mus musculus)
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uz9
Q-score: 0.289
Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ
Immunity (2022) 55 pp. 2419- [ Pubmed: 36370711 DOI: doi:10.1016/j.immuni.2022.10.019 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M8a-34 fab heavy chain (25 kDa, Protein from Mus musculus)
- Severe acute respiratory syndrome coronavirus 2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- M8a-34 fab light chain (23 kDa, Protein from Mus musculus)
- Sars-cov-2 s 6p in complex with m8a-34 fab (25 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- M8a-34 fab vh and vl domains (Complex from Mus musculus)
- M8a-34 fab ch1 and cl domains (Complex from Mus musculus)